Bleomycin sulfate cas no:9041-93-4
Synonyms: Bleomycin sulfate [Bleomycins];Bleomycine [INN-French];Bleomycin, sulfate;Bleomycin sulfate (JP14/USP);Bleomycins;3-[[2-[2-[2-[[(2S,3R)-2-[[(2S,3S,4R)-4-[[(2S,3R)-2-[[6-amino-2-[(1S)-1-[[(2S)-2-amino-2-carbamoyl-ethyl]amino]-2-carbamoyl-ethyl]-5-methyl-pyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(3H-imidazol-4-yl)propanoyl]amino]-3-hydroxy-2-methyl-pentanoyl]amino]-3-hydroxy-butanoyl]amino]ethyl]-1,3-thiazol-4-yl]1,3-thiazole-4-carbonyl]amino]propyl-dimethyl-sulfanium;Blexane;Bleomicin;Bleomycin,sulfate (salt);Bleomycin sulfate [USAN:JAN];Bleomycinsulfate;Blenoxane (TN);Bleomycinum [INN-Latin];Pingyangmyvin A2;Bleomicina [INN-Spanish];
NameBleomycin sulfate
CAS9041-93-4
SynonymsBleomycin sulfate [Bleomycins];Bleomycine [INN-French];Bleomycin, sulfate;Bleomycin sulfate (JP14/USP);Bleomycins;3-[[2-[2-[2-[[(2S,3R)-2-[[(2S,3S,4R)-4-[[(2S,3R)-2-[[6-amino-2-[(1S)-1-[[(2S)-2-amino-2-carbamoyl-ethyl]amino]-2-carbamoyl-ethyl]-5-methyl-pyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(3H-imidazol-4-yl)propanoyl]amino]-3-hydroxy-2-methyl-pentanoyl]amino]-3-hydroxy-butanoyl]amino]ethyl]-1,3-thiazol-4-yl]1,3-thiazole-4-carbonyl]amino]propyl-dimethyl-sulfanium;Blexane;Bleomicin;Bleomycin,sulfate (salt);Bleomycin sulfate [USAN:JAN];Bleomycinsulfate;Blenoxane (TN);Bleomycinum [INN-Latin];Pingyangmyvin A2;Bleomicina [INN-Spanish];
EINECS(EC#)232-925-2
Molecular FormulaC55H84N17O21S3.HSO4
Molecular Weight161.1989
Appearancewhite powder
storage temp2-8°C
Hazard T: Toxic;Xi: Irritant;
Risk R46
Safety
Hazard Codes:?
T,?
Xi
Risk Statements: 46-40-36/37/38?
R46:May cause heritable genetic damage.?
R40:Limited evidence of a carcinogenic effect.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 53-36/37-45-36-26
?S53:Avoid exposure - obtain special instructions before use.?
S36/37:Wear suitable protective clothing and gloves.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36:Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: EC5991990
F: 10
Poison by subcutaneous and intraperitoneal routes. Human systemic effects: cyanosis, allergic dermatitis. Questionable carcinogen with experimental carcinogenic data. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx. See other bleomycin entries.
| 1. |
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dnr-esc 20 μmol/L
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MUREAV ?? Mutation Research. 164 (1986),19. |
| 2. |
??? |
hma-mus/esc 10?mg/kg
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MUREAV ?? Mutation Research. 164 (1986),19. |
| 3. |
??? |
par-wmn TDLo:20?μg/kg:PUL,SKN
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ARHEAW ?? Arthritis and Rheumatism. 28 (1985),459. |
| 4. |
??? |
ipr-rat LD50:240?mg/kg
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??? |
IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 7 (1976),108. |
| 5. |
??? |
scu-rat LD50:86?mg/kg
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??? |
JJANAX ?? Japanese Journal of Antibiotics. 29 (1976),894. |
| 6. |
??? |
ipr-mus LD50:210?mg/kg
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??? |
YAKUD5 ?? Gekkan Yakuji. Pharmaceuticals Monthly. 17 (1975),455. |
| 7. |
??? |
scu-mus LD50:103?mg/kg
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??? |
JJANAX ?? Japanese Journal of Antibiotics. 29 (1976),894. |
