Bleomycinamide,N1-[4-[(aminoiminomethyl)amino]butyl]- cas no:9060-10-0

Synonyms: BleomycinB2; Dehydrophleomycin D1; Phleomycin D2; Zhengguangmycin B2

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Identification
Chemical Properties
Safety Data
Toxicity

Identification

NameBleomycinamide,N1-[4-[(aminoiminomethyl)amino]butyl]-
CAS9060-10-0
SynonymsBleomycinB2; Dehydrophleomycin D1; Phleomycin D2; Zhengguangmycin B2
Molecular FormulaC55H84 N20 O21 S2
Molecular Weight1425.71

Chemical Properties

refractive index1.768

Safety Data

Safety

Poison by intratracheal route. Mutation data reported. When heated to decomposition it emits toxic fumes of SO_x and NO_x. See other bleomycin entries.

Toxicity

1.	mmo-sat 1 µg/plate	MUREAV Mutation Research. 117 (1983),9.
2.	dnd-omi 100 mg/L	JANTAJ Journal of Antibiotics. 28 (1975),537.
3.	dnd-omi 10,700 pmol/L	CNREA8 Cancer Research. 40 (1980),4173.
4.	itr-mus LDLo:14 µg/kg	TXAPA9 Toxicology and Applied Pharmacology. 56 (1980),326.

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