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Sodium Hyaluronate cas no:9067-32-7

Synonyms: Hyaluronic acid sodium salt; Chlamyhyaluronic acid sodium salt; HA Sodium

Identification
NameSodium Hyaluronate
CAS9067-32-7
SynonymsHyaluronic acid sodium salt; Chlamyhyaluronic acid sodium salt; HA Sodium
EINECS(EC#)232-678-0
Molecular FormulaC28H44N2O23?Na
Molecular Weight799.6366
Chemical Properties
Appearancesolid
storage temp?20°C
Safety Data

Hazard Xi: Irritant;
Risk 36/37/38
Safety

Hazard Codes:?BiohazardB,IrritantXi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-36/37/39-27-26?
S22:Do not breathe dust.?
S24/25:Avoid contact with skin and eyes.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S27:Take off immediately all contaminated clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: MT7250000
F: 3-10
Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of Na2O.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 subcutaneous > 50mg/kg (50mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19(Suppl,
mouse LD50 intraperitoneal 1500mg/kg (1500mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 1013, 1984.
mouse LD50 oral > 2400mg/kg (2400mg/kg) ? Drugs in Japan Vol. -, Pg. 849, 1990.
mouse LD50 subcutaneous > 4gm/kg (4000mg/kg) BEHAVIORAL: ATAXIA Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
rabbit LD50 intraperitoneal 1820mg/kg (1820mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BLOOD: NORMOCYTIC ANEMIA
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
rabbit LD50 oral > 1gm/kg (1000mg/kg) ? Drugs in Japan Vol. -, Pg. 849, 1990.
rabbit LD50 subcutaneous > 2gm/kg (2000mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
rat LD50 intraperitoneal 1770mg/kg (1770mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BLOOD: NORMOCYTIC ANEMIA
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
rat LD50 oral > 800mg/kg (800mg/kg) ? Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
rat LD50 subcutaneous > 4gm/kg (4000mg/kg) BEHAVIORAL: ATAXIA Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.

supplier list

Nanjing Elegant Nutraceuticals Co.,Ltd.
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Address: Room A233, Weifen Hotel,28 North Yunnan Road,Nanjing The P. R. China
Shangyu Zhongchang Chemical Co.,LTD.
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Address: Shangyu chemical zone,zhejiang,China
China Chem Source (HK) Co.,Ltd
Tel:+86-411-82808830 82649412 82649140 82647982 82659338
Address: Room 1818, The Bank of East Asia Mansion , Dalian , 116001, China.
ZunAn Commerce & Industrial Co., Ltd.
Tel:锛?86-755-82910159, 82910995,82910996
Address: Room 3007, United Plaza A, Binhe Road 5022, Shenzhen, P.R.China
HANGZHOU THINK CHEMICAL CO., LTD.
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Address: ROOM 719 BUILDING D MEIDU PLAZA 789 MOGANSHAN ROAD HANGZHOU CHINA
Yantai Dongcheng Biochemical Co., Ltd.
Tel:+86-(535)-637-3853, 637-8569, 637-0505
Address: No.7 Changbaishan Road, Yantai Development Zone, ShanDong 264006,
Hangzhou Gallop Biological Products Co. Ltd.
Tel:+86-(571)-88913735,88913732
Address: Block B,Floor 2,No.3 Workshop,Jieneng industrial estate, Hangzhou 310012,
Shanghai Chemhere Co., Ltd.
Tel:+86-(21)-26607989
Address: Unit 602, No.14,Ziwei Rd, Zhangjiang High-tech Park, Shanghai,
Jiangyin Healthway International Trade Co., Ltd
Tel:+86-(510)-86023169
Address: 7-305, 2(W) Binjiang Road, Jiangyin City, Jiangsu 214433,
Alcan Chemicals Division
Tel:1-203- 5419000
Address: Stamford Harbor Park, North Tower, 333 Ludlow Street, Stamford, Connecticut 06902,
Austin Chemical Company, Inc.
Tel:+1-(847)-520 9600
Address: 1565 Barclay Blvd., Buffalo Grove, Illinois 60089,
AIDP, Inc.
Tel:+1-(626)-964 6910
Address: 17920 East Ajax Circle, City of Industry, California 91748,
Jiagen Biotechnologies Inc.
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QuFu GuangLong Biochemical Co., Ltd.
Tel:+86-(537)-4436374/4436379
Address: No.1 GuangMing Road, QuFu Economic Zone, QuFu, ShanDong,
Eastar Holding Group Co Ltd.
Tel:+86-(546)-2061256
Address: No.98 Yongshen Road.,Shengtuo Town,Kenli Country, Dongying, Shandong 257506,

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