9067-32-7|Sodium HyaluronateProducts Supply - Chemical intermediates Network

Sodium Hyaluronate cas no:9067-32-7

Synonyms: Hyaluronic acid sodium salt; Chlamyhyaluronic acid sodium salt; HA Sodium

Identification

NameSodium Hyaluronate
CAS9067-32-7
SynonymsHyaluronic acid sodium salt; Chlamyhyaluronic acid sodium salt; HA Sodium
EINECS(EC#)232-678-0
Molecular FormulaC28H44N2O23?Na
Molecular Weight799.6366

Chemical Properties

Appearancesolid
storage temp?20°C

Safety Data

Hazard Xi: Irritant;
Risk 36/37/38
Safety

Hazard Codes:? Biohazard B, Irritant Xi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-36/37/39-27-26?
S22:Do not breathe dust.?
S24/25:Avoid contact with skin and eyes.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S27:Take off immediately all contaminated clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: MT7250000
F: 3-10
Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of Na₂O.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	subcutaneous	> 50mg/kg (50mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19(Suppl,
mouse	LD50	intraperitoneal	1500mg/kg (1500mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 1013, 1984.
mouse	LD50	oral	> 2400mg/kg (2400mg/kg)	?	Drugs in Japan Vol. -, Pg. 849, 1990.
mouse	LD50	subcutaneous	> 4gm/kg (4000mg/kg)	BEHAVIORAL: ATAXIA	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
rabbit	LD50	intraperitoneal	1820mg/kg (1820mg/kg)	LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BLOOD: NORMOCYTIC ANEMIA	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
rabbit	LD50	oral	> 1gm/kg (1000mg/kg)	?	Drugs in Japan Vol. -, Pg. 849, 1990.
rabbit	LD50	subcutaneous	> 2gm/kg (2000mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
rat	LD50	intraperitoneal	1770mg/kg (1770mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BLOOD: NORMOCYTIC ANEMIA	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
rat	LD50	oral	> 800mg/kg (800mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.
rat	LD50	subcutaneous	> 4gm/kg (4000mg/kg)	BEHAVIORAL: ATAXIA	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12, Pg. 5369, 1984.

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Sodium Hyaluronate cas no:9067-32-7

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