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2H-1-Benzopyran-2-one,7-hydroxy-6-methoxy- cas no:92-61-5

Synonyms: Coumarin,7-hydroxy-6-methoxy- (8CI);6-Methoxy-7-hydroxycoumarin;6-Methylesculetin;6-O-Methylesculetin;7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one;7-Hydroxy-6-methoxycoumarin;Buxuletin;Chrysatropic acid;Escopoletin;Esculetin 6-methyl ether;Gelseminic acid;Murrayetin;NSC 405647;Scopoletin;Scopoletine;Scopoletol;b-Methylesculetin;

Identification
Name2H-1-Benzopyran-2-one,7-hydroxy-6-methoxy-
CAS92-61-5
SynonymsCoumarin,7-hydroxy-6-methoxy- (8CI);6-Methoxy-7-hydroxycoumarin;6-Methylesculetin;6-O-Methylesculetin;7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one;7-Hydroxy-6-methoxycoumarin;Buxuletin;Chrysatropic acid;Escopoletin;Esculetin 6-methyl ether;Gelseminic acid;Murrayetin;NSC 405647;Scopoletin;Scopoletine;Scopoletol;b-Methylesculetin;
EINECS(EC#)202-171-9
Molecular FormulaC10H8O4
Molecular Weight192.17
Chemical Properties
Appearanceyellow to beige crystalline powder
refractive index1.609
storage tempKeep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Hazard Codes of 2H-1-Benzopyran-2-one,7-hydroxy-6-methoxy- (CAS NO.92-61-5): IrritantXi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36: Wear suitable protective clothing. 
S37/39: Wear suitable gloves and eye/face protection.
WGK Germany: 2
RTECS: GN6930000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 350mg/kg (350mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1330, 1968.
rat LD50 oral 3800mg/kg (3800mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 210, Pg. 27, 1974.

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