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5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-,sodium salt (1:1), (6R,7R)- cas no:92823-03-5

Synonyms: 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-,monosodium salt, (6R,7R)- (9CI); 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-,monosodium salt, (6R-cis)-; 6315 S Shionogi; 6315S; Flomoxef sodium; Flomoxefsodium salt; Flumarin

Identification
Name5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-,sodium salt (1:1), (6R,7R)-
CAS92823-03-5
Synonyms5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-,monosodium salt, (6R,7R)- (9CI); 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-,monosodium salt, (6R-cis)-; 6315 S Shionogi; 6315S; Flomoxef sodium; Flomoxefsodium salt; Flumarin
Molecular FormulaC15H18 F2 N6 O7 S2 . Na
Molecular Weight518.45
Safety Data

Safety

Moderately toxic by intravenous route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx, SOx, F−, and Cl−.


Toxicity
1.    

ivn-rat LD50:7360 mg/kg

    NKRZAZ    Chemotherapy (Tokyo). 35 (Suppl 1)(1987),207.
2.    

scu-mus LD50:13,500 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.
3.    

ivn-mus LD50:7086 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.

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