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Glimepiride cas no:93479-97-1

Synonyms: 1h-pyrrole-1-carboxamide,2,5-dihydro-3-ethyl-4-methyl-n-(2-(4-(((((4-methylcyc; glimepirid; hoe490; trans-lohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo; 1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea; amary; AMARYL; Glimpiride

Identification
NameGlimepiride
CAS93479-97-1
Synonyms1h-pyrrole-1-carboxamide,2,5-dihydro-3-ethyl-4-methyl-n-(2-(4-(((((4-methylcyc; glimepirid; hoe490; trans-lohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo; 1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea; amary; AMARYL; Glimpiride
Molecular FormulaC24H34N4O5S
Molecular Weight490.62
Chemical Properties
AppearanceWhite Cyrstalline Solid
refractive index1.599
storage tempRoom temp
Safety Data

Hazard Xn,Xi
Risk R21
Safety

Hazard Codes:?HarmfulXn,IrritantXi
Risk Statements: 21-36/38-46-62-63?
R21:Harmful in contact with skin.?
R36/38:Irritating to eyes and skin.?
R46:May cause heritable genetic damage.?
R62:Risk of impaired fertility.?
R63:Possible risk of harm to the unborn child.
Safety Statements: 25-26-36/37-53
S25:Avoid contact with eyes.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37:Wear suitable protective clothing and gloves.?
S53:Avoid exposure - obtain special instructions before use.
WGK Germany: 3
RTECS: UX9363950


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 28ug/kg/2D-I (0.028mg/kg) BLOOD: HEMORRHAGE
BLOOD: THROMBOCYTOPENIA
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Annals of Pharmacotherpy. Vol. 34, Pg. 120, 2000.
mouse LD50 unreported > 10gm/kg (10000mg/kg) ? Diabetes Frontier. Vol. 3, Pg. 565, 1992.
rat LD intraperitoneal > 3950mg/kg (3950mg/kg) LIVER: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 43, Pg. 547, 1993.
rat LD oral > 10gm/kg (10000mg/kg) LIVER: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 43, Pg. 547, 1993.
rat LD50 unreported > 10gm/kg (10000mg/kg) ? Diabetes Frontier. Vol. 3, Pg. 565, 1992.

supplier list

Tianjin Harmony Technology Development Co., Ltd.
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Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China
CNCCC SICHUAN IMPORT/EXPORT CO.,LTD.
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Address: 8C Ruili, Palm Garden, 153 KeHua North Rd, Chengdu,Sichuan, P.R.China
Amoy Cpharma Company Limited
Tel:+86-592-2283485 , 2283719 , 2283739
Address: No. 862 Xiahe Road, Unit 8D of Jinshan Building, Xiamen China
Shangyu Zhongchang Chemical Co.,LTD.
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Address: Shangyu chemical zone,zhejiang,China
Luna Chemicals Co.,Ltd.
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Address: 1502-1503,No.310 North Zhong Shan Rd., Hangzhou,China
Nexchem Pharmaceutical Co.,Ltd.
Tel:0086-579-82207640 83182935 83188860
Address: No.1318 Jinsha road, Linjiang industrial zone, Wucheng area, Jinhua city,Zhejiang Province, China. and Dongxi industrial zone
Zhejiang Jiangbei Pharmaceutical Co.,Ltd.
Tel:86-576-88786518 86-21-62183156
Address: Dongdai Dock Zhangan Street Jiaojiang District Taizhou City Zhejiang Province ,China
Chongqing World Haorui Pharm-Chem Co., Ltd.
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Address: Yongqing Industrial,Tongliang County,Chongqing,China.
Zhejiang Medicines & Health Products Import & Exp...
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Address: ZMC Building,101-2 N. Zhongshan Road,Hangzhou,China.
THYKN (INDIA) INTERNATIONAL
Tel:+91-22-67033666 (3 lines)
Address: 202, Kuntal, Mody Estate, Nr.Pipeline, LBS Road, Ghatkopar (West), Mumbai - 400086, India
Ancheng Pharma Limited
Tel:+86-755-82713308
Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China
TRITON CHEMTECH CO., LTD.
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Address: Room 717, 7/F, Information Tower, 1403 Minsheng Road, Shanghai, 200135, China
Pharmasi Chemicals Co.,Ltd
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Address: Room 205, Renlesancun50-29,songjiang,shanghai,China
Sunji & Co., Ltd.
Tel:86-755-8825 1355 /1365 /1379
Address: Room 2103-2104, Block C , Huangdu Plaza, 3008 Yitian Road, Shenzhen 518048, P.R. of China
CHONGQING TRUST LONG CO.,LTD.
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Address: 3-6-2, No.1, Xinglong Road, Longxi Town, Yubei Dist.,Chongqing,China

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