93793-83-0|Roxatidine acetate hydrochlorideProducts Supply

Roxatidine acetate hydrochloride cas no:93793-83-0

Synonyms: Altat (TN);Roxatidine acetate hydrochloride (JAN/USAN);Acetamide,2-(acetyloxy)-N-[3-[3-(1- piperidinylmethyl)phenoxy]propyl]-,monohydrochloride;Altat;Roxatidine aceacetate HCl;Acetamide,2-(acetyloxy)-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-monohydrochloride;Roxatidine Acetate HCl;

Identification

NameRoxatidine acetate hydrochloride
CAS93793-83-0
SynonymsAltat (TN);Roxatidine acetate hydrochloride (JAN/USAN);Acetamide,2-(acetyloxy)-N-[3-[3-(1- piperidinylmethyl)phenoxy]propyl]-,monohydrochloride;Altat;Roxatidine aceacetate HCl;Acetamide,2-(acetyloxy)-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-monohydrochloride;Roxatidine Acetate HCl;
Molecular FormulaC₁₉H₂₈N₂O₄^.ClH
Molecular Weight384.9

Safety Data

Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x and HCl. See also ESTERS.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	75mg/kg (75mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 1167, 1985.
dog	LD50	oral	100mg/kg (100mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 1167, 1985.
monkey	LD50	intravenous	50mg/kg (50mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 1167, 1985.
mouse	LD50	intravenous	83mg/kg (83mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 1167, 1985.
mouse	LD50	oral	509mg/kg (509mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 1167, 1985.
mouse	LD50	subcutaneous	384mg/kg (384mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 1167, 1985.
rabbit	LD50	oral	900mg/kg (900mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 1167, 1985.
rat	LD50	intraperitoneal	227mg/kg (227mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 1167, 1985.
rat	LD50	intravenous	110mg/kg (110mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 1167, 1985.
rat	LD50	oral	755mg/kg (755mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 1167, 1985.
rat	LD50	subcutaneous	595mg/kg (595mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 1167, 1985.

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SUNWELL CHEMICALS CO.,LTD.(INTERPHARMA TRADING CO...: Tel:; Address: SUITE 1108,GOLDEN PLAZA,NO.118,QING CHUN ROAD,HANGZHOU,ZHEJIANG,CHINA

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XINGXIN BIOCHEMICAL CO., LTD: Tel:; Address: Sijuxia St. Hechuan Chongqing, P.R. China.

Hetero Drugs Ltd.,: Tel:+91-(40)-23704923; Address: H.No. 8-3-166/7/1, Erragadda, Hyderabad, Andhra Pradesh 500 018,

Jinan Chenghui-Shuangda Chemical Co., Ltd.: Tel:+86-531-82312537 82312560 82312509; Address: 2nd Floor, Capital High & New Industry Base, No.15 Huaxin R.D., Jinan

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American Custom Chemicals Corporation: Tel:+1-(858)-201-6118; Address: P.O Box 910574, San Diego, California 92191-0574,

Changzhou Xixialong International Co., Ltd.: Tel:+86-(519)-8512-0628; Address: Room.5002, Modern City, No.217 Huangshan Road, Changzhou, Jiangsu 213022,

Zhejiang Tongfeng Chemical Factory: Tel:+86-(576)-5991250,5991251; Address: Xunqiao, Linhai, Zhejiang 317024,

Hangzhou Meite Chemical Co., Ltd.: Tel:+86-(571)-8802-6825, 8828-3817; Address: 58#, Xinjian Road, Chemical Industrial Zone of Hangzhou, Gulf Economic Development District, Hangzhou,

ALL PRO CORPORATION: Tel:86-532-82850205; Address: No.592, TONGHE ROAD, QINGDAO, CHINA

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Roxatidine acetate hydrochloride cas no:93793-83-0

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