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6-Nitrobenzimidazole cas no:94-52-0

Synonyms: 5-Nitro-1H-benzimidazole; 5-Nitrobenzimidazole nitrate salt

Identification
Name6-Nitrobenzimidazole
CAS94-52-0
Synonyms5-Nitro-1H-benzimidazole; 5-Nitrobenzimidazole nitrate salt
EINECS(EC#)202-341-2
Molecular FormulaC7H5N3O2
Molecular Weight163.14
Chemical Properties
Appearanceyellow to green crystals
refractive index1.74
storage tempStore in a cool, dry place. Store in a tightly closed container.
Safety Data

Hazard Xn:Harmful;
Risk R22;R40
Safety

Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITRO COMPOUNDS of AROMATIC HYDROCARBONS.
Hazard Codes: XiIrritant,XnHarmful
Risk Statements: 36/37/38-40-22
36/37/38:  Irritating to eyes, respiratory system and skin 
40:  Limited evidence of a carcinogenic effect 
22:  Harmful if swallowed 
Safety Statements: 26-45-36/37
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
36/37:  Wear suitable protective clothing and gloves  
RIDADR: 2811
WGK Germany: 3
RTECS: DD9800000
HS Code: 29339990


HS Code 29339990

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 185mg/kg (185mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: IRRITABILITY

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 57, Pg. 460, 1961.
mouse LD50 intravenous 35mg/kg (35mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 135, Pg. 364, 1962.
mouse LD50 oral 140mg/kg (140mg/kg)   Therapie. Vol. 26, Pg. 1203, 1971.
mouse LD50 subcutaneous 260mg/kg (260mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 135, Pg. 364, 1962.

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