2,6-Pyridinediamine,3-(2-phenyldiazenyl)- cas no:94-78-0
Synonyms: 2,6-Pyridinediamine,3-(phenylazo)- (9CI);Pyridine, 2,6-diamino-3-(phenylazo)- (6CI,7CI,8CI);2,6-Diamino-3-phenylazopyridine;Gastracid;Gastrotest;NSC 145895;Phenazopyridine;3-Phenylazopyridine-2,6-diamine;
Name2,6-Pyridinediamine,3-(2-phenyldiazenyl)-
CAS94-78-0
Synonyms2,6-Pyridinediamine,3-(phenylazo)- (9CI);Pyridine, 2,6-diamino-3-(phenylazo)- (6CI,7CI,8CI);2,6-Diamino-3-phenylazopyridine;Gastracid;Gastrotest;NSC 145895;Phenazopyridine;3-Phenylazopyridine-2,6-diamine;
EINECS(EC#)202-363-2,
205-243-8
Molecular FormulaC11H11N5
Molecular Weight213.24
Appearancedark red to violet crystalline powder
Hazard UN NO.
Safety
The safety information of Phenazopyridine (CAS NO.94-78-0):
Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental neoplastigenic data. Used as a local anesthetic. When heated to decomposition it emits toxic fumes of NOx.
The toxicity of Phenazopyridine (CAS NO.94-78-0):
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| man |
TDLo |
oral |
4693mg/kg/3Y- (4693mg/kg) |
KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION
BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN
SKIN AND APPENDAGES (SKIN): NAILS: OTHER |
Annals of Internal Medicine. Vol. 127, Pg. 1137, 1997. |
| mouse |
LD50 |
oral |
580mg/kg (580mg/kg) |
|
Pharmaceutica Acta Helvetiae. Vol. 35, Pg. 423, 1960. |
| rat |
LD50 |
intraperitoneal |
560mg/kg (560mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Journal of Pharmacology and Experimental Therapeutics. Vol. 51, Pg. 200, 1934. |
