Benzenesulfonamide,N-[[(4,6-dimethoxy-1,3,5-triazin-2-yl)amino]carbonyl]-2-(2-methoxyethoxy)- cas no:94593-91-6
Synonyms: CGA 142464;Dimetrasulfuron;Set-off;
NameBenzenesulfonamide,N-[[(4,6-dimethoxy-1,3,5-triazin-2-yl)amino]carbonyl]-2-(2-methoxyethoxy)-
CAS94593-91-6
SynonymsCGA 142464;Dimetrasulfuron;Set-off;
Molecular FormulaC15H19N5O7S
Molecular Weight413.4
Appearancecolorless crystalline powder
refractive index1.57
storage temp0-6°C
Safety
mammalian toxicology
Oral Acute oral LD50 for rats 4102 mg/kg. Skin and eye Acute percutaneous LD50 for rabbits >2000 mg/kg. Not a skin irritant or eye irritant (rabbits). Not a skin sensitiser (guinea pigs). Inhalation LC50 (4 h) for rats >5 mg/l air. NOEL (2 y) for rats 250 mg/kg diet (12.5 mg/kg daily); (1 y) for dogs 250 mg/kg diet (6.25 mg/kg daily). NOEL in: reproduction (2-generation) in rats 250 mg/kg diet; teratogenicity in rats 30, rabbits 15 mg/kg. ADI 0.020 mg/kg b.w. Toxicity class WHO (a.i.) III (Table 5); EPA (formulation) III
ecotoxicology
Birds Acute oral LD50 (14 d) for mallard ducks >2510 mg/kg. Dietary LC50 for mallard ducks and bobwhite quail >5620 ppm. Fish LC50 (96 h) for trout >1000, bluegill sunfish >100 mg/l. Daphnia LC50 (48 h) 1000 mg/l. Other aquatic spp. For Lemna gibba, EbC50 0.45 ppb, ErC50 45 mg/l, EC50 (frond counts) 0.27 ppb. LC50 for crayfish >1000 ppm. Bees LD50 (48 h) >12.5 mg/bee. Worms LC50 for earthworms (Eisenia foetida) >4050 mg/kg.
environmental fate
Animals Cinosulfuron (94593-91-6) is rapidly and extensively metabolised in the hen; 18 metabolites in the excreta were resolved by hplc. Soil/Environment In soil, Kd >1.60 (pH 4.5, 5.6% o.m.), 0.28 (pH 5.8, 4.3 % o.m.), <0.03 (pH 6.5, 2.1% o.m.), <0.03 (pH 6.6, 1.1 % o.m.).
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
oral |
> 10368mg/kg (10368mg/kg) |
|
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 17, Pg. S165, 1992. |
| quail |
LD50 |
oral |
> 2gm/kg (2000mg/kg) |
|
Pesticide Manual. Vol. 9, Pg. 174, 1991. |
| rat |
LC50 |
inhalation |
> 5574mg/m3/4H (5574mg/m3) |
|
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 17, Pg. S165, 1992. |
| rat |
LD50 |
oral |
> 10368mg/kg (10368mg/kg) |
|
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 17, Pg. S165, 1992. |
| rat |
LD50 |
skin |
> 5gm/kg (5000mg/kg) |
|
Pesticide Manual. Vol. 9, Pg. 174, 1991. |
