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2,5-Diaminotoluene cas no:95-70-5

Synonyms: Toluene-2,5-diamine(7CI,8CI);1,4-Diamino-2-methylbenzene;1-Methyl-2,5-diaminobenzene;2,5-Diaminotoluol;2-Methyl-1,4-benzenediamine;2-Methyl-1,4-phenylenediamine;2-Methyl-p-phenylenediamine;4-Amino-2-methylaniline;4-Amino-3-methylaniline;1,4-Benzenediamine,2-methyl-;Toluylene-2,5-diamine;p-Toluenediamine;

Identification
Name2,5-Diaminotoluene
CAS95-70-5
SynonymsToluene-2,5-diamine(7CI,8CI);1,4-Diamino-2-methylbenzene;1-Methyl-2,5-diaminobenzene;2,5-Diaminotoluol;2-Methyl-1,4-benzenediamine;2-Methyl-1,4-phenylenediamine;2-Methyl-p-phenylenediamine;4-Amino-2-methylaniline;4-Amino-3-methylaniline;1,4-Benzenediamine,2-methyl-;Toluylene-2,5-diamine;p-Toluenediamine;
EINECS(EC#)202-442-1
Molecular FormulaC7H10N2
Molecular Weight122.17
Chemical Properties
AppearancePlates from benzene.
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T: Toxic;N: Dangerous for the environment;
Risk R20/21
Safety

Poison by ingestion and subcutaneous routes. A skin irritant. Mutation data reported. Questionable carcinogen. Has a toxic action upon the liver and can cause fatty degeneration of that organ. Its total effect upon the body seems to take place three different ways. It is toxic to the central nervous system, producing jaundice by action on the liver and spleen, and anemia by destruction of the red blood cells. This action is quite similar to that of aniline, although by no means identical with it. Its high boiling point and the fact that the material is solid at room temperature make it somewhat less hazardous than aniline, particularly at ordinary working temperatures. The literature contains a reference to a permanent injury to an eye due to the use of this material as an eyelash dye. It is considered to be an irritating dye material. When heated to decomposition it emits toxic fumes of NOx. 
Hazard Codes: ToxicT,DangerousN
Risk Statements: 20/21-25-43-51/53 
R20/21: Harmful by inhalation and in contact with skin. 
R25: Toxic if swallowed. 
R43: May cause sensitization by skin contact. 
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 24-37-45-61 
S24: Avoid contact with skin. 
S37: Wear suitable gloves. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
HazardClass: 6.1(b)
PackingGroup of 2,5-Diaminotoluene (CAS NO.95-70-5): III


Toxicity
1.    

skn-rbt 12,500 µg/24H MLD

    FCTXAV    Food and Cosmetics Toxicology. 15 (1977),607.
2.    

mma-sat 100 µg/plate

    PNASA6    Proceedings of the National Academy of Sciences of the United States of America. 72 (1975),2423.
3.    

dns-rat:lvr 10 µmol/L

    MUREAV    Mutation Research. 136 (1984),255.
4.    

dni-mus-ipr 40 mg/kg

    MRLEDH    Mutation Research Letters. 91 (1981),75.
5.    

dns-ham:lvr 10 µmol/L

    MUREAV    Mutation Research. 136 (1984),255.
6.    

orl-rat LD50:102 mg/kg

    FCTXAV    Food and Cosmetics Toxicology. 15 (1977),607.
7.    

scu-rat LDLo:50 mg/kg

    ZEPTAT    Zeitschrift fuer Experimentelle Pathologie und Therapie. 17 (1915),59.
8.    

scu-rbt LDLo:100 mg/kg

    ZEPTAT    Zeitschrift fuer Experimentelle Pathologie und Therapie. 17 (1915),59.
9.    

orl-mam LDLo:3600 mg/kg

    JIDHAN    Journal of Industrial Hygiene. 13 (1931),87.

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