Phencyclidine hydrochloride cas no:956-90-1

NamePhencyclidine hydrochloride
CAS956-90-1
SynonymsCI395;CI-395;Piperidine, 1-(1-phenylcyclohexyl)-, hydrochloride;C.I. 395;PCP hydrochloride;Piperidine, 1- (1-phenylcyclohexyl)-, hydrochloride;GP 121;MCV 4158;Elysion;Phencyclidine hydrochloride [USAN];Sernyl;DEA No. 7471;Peace pill;NIH 9580;Cl 395 hydrochloride;CN-25,253-2;Elephant tranquilizer;Trank;GP-121;DOA;Sernyl hydrochloride;1-(1-Phenylcyclohexyl)piperidine hydrochloride;Pcp;1-(1-phenylcyclohexyl)-3,4,5,6-tetrahydro-2H-pyridine chloride;Phenylcyclidine hydrochloride;Sernylan;Piperidine,1-(1-phenylcyclohexyl)-,hydrochloride;1-(1-phenylcyclohexyl)piperidine;NSC-40902;
Molecular FormulaC₁₇H₂₅N•ClH
Molecular Weight279.89

storage tempStore at RT

Hazardclass6.1(a)

Hazard T
Risk 25
Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by ingestion and intravenous routes: distorted perceptions, euphoria, excitement, hallucinations, and paresthesia. An experimental teratogen. Other experimental reproductive effects. Often mixed with other drugs of abuse yielding totally unpredictable effects. A controlled substance. When heated to decomposition it emits very toxic fumes of HCl and NO_x.
Hazard Codes: T
Risk Statements: 25
R25: Toxic if swallowed.
Safety Statements: 36/37-45
S36/37: Wear suitable protective clothing and gloves. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: TN2272600
HazardClass: 6.1(a)
PackingGroup: I

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	5600ug/kg (5.6mg/kg)		Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
dog	LDLo	intravenous	50mg/kg (50mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD CARDIAC: CHANGE IN RATE VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION	Toxicology. Vol. 19, Pg. 11, 1981.
duck	LD50	oral	75mg/kg (75mg/kg)		Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
human	LDLo	oral	14mg/kg (14mg/kg)	BEHAVIORAL: COMA	JAMA, Journal of the American Medical Association. Vol. 238, Pg. 515, 1977.
human	TDLo	intravenous	10ug/kg (0.01mg/kg)	PERIPHERAL NERVE AND SENSATION: PARESTHESIS BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"	Canadian Psychiatric Association Journal. Vol. 6, Pg. 150, 1961.
human	TDLo	oral	71ug/kg (0.071mg/kg)	BEHAVIORAL: EUPHORIA BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: EXCITEMENT	JAMA, Journal of the American Medical Association. Vol. 238, Pg. 515, 1977.
mouse	LD50	intraperitoneal	59558ug/kg (59.558mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ATAXIA	Substance and Alcohol Actions/Misuse. Vol. 2, Pg. 143, 1981.
mouse	LD50	intravenous	16mg/kg (16mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Life Sciences. Vol. 31, Pg. 803, 1982.
mouse	LD50	oral	77mg/kg (77mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 28, Pg. 713, 1976.
mouse	LD50	subcutaneous	43mg/kg (43mg/kg)		Journal of Medicinal Chemistry. Vol. 24, Pg. 496, 1981.
pigeon	LD50	oral	237mg/kg (237mg/kg)		Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
rat	LD50	oral	135mg/kg (135mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)	Neurobehavioral Toxicology and Teratology. Vol. 3, Pg. 11, 1981.