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Safety
Poison by ingestion, intraperitoneal, subcutaneous, intramuscular, and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl. Used as an antihistamine.
1. |
orl-rat LD50:525 mg/kg |
29ZVAB Handbook of Analytical Toxicology ,Sunshine, I., ed.,Cleveland, OH.: Chemical Rubber Co.,1969,113. | ||
2. |
ivn-rat LD50:15 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 97 (1949),371. | ||
3. |
orl-mus LD50:277 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 97 (1949),371. | ||
4. |
ipr-mus LD50:55 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 97 (1949),371. | ||
5. |
scu-mus LD50:36 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 97 (1949),371. | ||
6. |
ivn-mus LD50:12,200 µg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 97 (1949),371. | ||
7. |
orl-dog LD50:60 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 97 (1949),371. | ||
8. |
ivn-dog LD50:10 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 97 (1949),371. | ||
9. |
ims-dog LD50:12 mg/kg |
JPETAB Journal of Pharmacology and Experimental Therapeutics. 97 (1949),371. | ||
10. |
ivn-rbt LD50:12 mg/kg |
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