Meropenem cas no:96036-03-2
Synonyms: 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid,3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-,(4R,5S,6S)-;1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid,3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-,[4R-[3(3S*,5S*),4a,5b,6b(R*)]]-;Antibiotic SM 7338;ICI 194660;Mepem;Meronem;Meropen;Merrem;Merrem IV;SM 7338;
NameMeropenem
CAS96036-03-2
Synonyms1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid,3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-,(4R,5S,6S)-;1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid,3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-,[4R-[3(3S*,5S*),4a,5b,6b(R*)]]-;Antibiotic SM 7338;ICI 194660;Mepem;Meronem;Meropen;Merrem;Merrem IV;SM 7338;
Molecular FormulaC17H25N3O5S
Molecular Weight383.46
AppearanceWhite or almost white powder Complies
refractive index1.639
Hazard Xi: Irritant;
Risk R36/37/38
Safety
Hazard Codes:?
Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S37/39:Wear suitable gloves and eye/face protection.
?
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LDLo |
intravenous |
2gm/kg (2000mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA |
Chemotherapy Vol. 40(Suppl, |
| mouse |
LD50 |
intravenous |
2650mg/kg (2650mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
BEHAVIORAL: ATAXIA |
Chemotherapy Vol. 40(Suppl, |
| mouse |
LD50 |
oral |
> 5gm/kg (5000mg/kg) |
? |
Chemotherapy Vol. 40(Suppl, |
| mouse |
LD50 |
subcutaneous |
> 5gm/kg (5000mg/kg) |
? |
Chemotherapy Vol. 40(Suppl, |
| rat |
LD50 |
intravenous |
2850mg/kg (2850mg/kg) |
PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Chemotherapy Vol. 40(Suppl, |
| rat |
LD50 |
oral |
> 5gm/kg (5000mg/kg) |
? |
Chemotherapy Vol. 40(Suppl, |
| rat |
LD50 |
subcutaneous |
> 5gm/kg (5000mg/kg) |
? |
Chemotherapy Vol. 40(Suppl, |
