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Piperidine,4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride (1:1) cas no:969-33-5

Synonyms: Piperidine,4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride (8CI,9CI);Ciplactin;Nuran;Periactin;Periactin hydrochloride;Periactin syrup;Peritol;Practin;Triactin;VUFB 3511;

Identification
NamePiperidine,4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride (1:1)
CAS969-33-5
SynonymsPiperidine,4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride (8CI,9CI);Ciplactin;Nuran;Periactin;Periactin hydrochloride;Periactin syrup;Peritol;Practin;Triactin;VUFB 3511;
EINECS(EC#)213-535-1
Molecular FormulaC21H21N.HCl
Molecular Weight323.89
Chemical Properties
storage tempStore at RT
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;
Risk R22;R36/37/38
Safety

Poison by ingestion and intraperitoneal routes. Human systemic effects by ingestion: jaundice, liver function tests impaired, gastrointestinal effects. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Safety Information about Cyproheptadine hydrochloride (CAS NO.969-33-5):
Hazard Codes: 
Xn:
Risk Statements about Cyproheptadine hydrochloride (CAS NO.969-33-5):
R22: Harmful if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about Cyproheptadine hydrochloride (CAS NO.969-33-5):
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: TM7050000
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1.    

cyt-hmn:lyms 2200 µmol/L/24H-C

    ZEKIA5    Zeitschrift fuer Kinderheilkunde. 118 (1974),219.
2.    

orl-wmn TDLo:7 mg/kg/4W-C:GIT,LIV

    BMJOAE    British Medical Journal. 1 (1978),753.
3.    

orl-rat LD50:295 mg/kg

    DRUGAY    Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),340.
4.    

ipr-rat LD50:52,400 µg/kg

    YAKUD5    Gekkan Yakuji. Pharmaceuticals Monthly. 22 (1980),375.
5.    

orl-mus LD50:69 mg/kg

    AGACBH    Agents and Actions, A Swiss Journal of Pharmacology. 4 (1974),264.
6.    

ipr-mus LD50:55,300 µg/kg

    YAKUD5    Gekkan Yakuji. Pharmaceuticals Monthly. 22 (1980),375.

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