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Hazard Xn
Risk 63-20/21/22
Safety
Poison by subcutaneous and intravenous routes. Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. See also SULFATES. When heated to decomposition it emits very toxic fumes of SOx and NOx.
Hazard Codes of 5-Hydroxytryptamine creatinine sulfate (CAS NO.971-74-4): Xn
Risk Statements: 63-20/21/22
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R63:Possible risk of harm to the unborn child.
Safety Statements: 36/37-24/25-22
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
S36/37:Wear suitable protective clothing and gloves.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | intravenous | 28mg/kg (28mg/kg) | LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION | Journal of Pharmaceutical Sciences. Vol. 57, Pg. 1543, 1968. |
mouse | LD50 | intraperitoneal | 405mg/kg (405mg/kg) | Yakugaku Zasshi. Journal of Pharmacy. Vol. 94, Pg. 1620, 1974. | |
mouse | LD50 | intravenous | 352mg/kg (352mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 80, 1952. | |
mouse | LD50 | subcutaneous | > 1997mg/kg (1997mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 80, 1952. | |
rat | LD50 | intravenous | 66mg/kg (66mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 80, 1952. | |
rat | LD50 | subcutaneous | 257mg/kg (257mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 80, 1952. |
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