Pyrazinamide cas no:98-96-4
Synonyms: Pyrazinamide (TN);Pirazinamid;Pirazimida;D-50;T 165;Novamid;NCI-C01785;Pyrazineamide;MK 56;2-Carbamylpyrazine;D-50 (VAN);Pirazinamida [INN-Spanish];Pirazinamide [DCIT];PZA;2-Pyrazinecarboxamide;1/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9;Pyrazinamide (JP14/USP);5-25-04-00178 (Beilstein Handbook Reference);Prestwick_811;Zinamide;Pyrazinamidum [INN-Latin];PYZ;Pyrazinecarboxylic acid amide;Aldinamide;Pyrazinamide [BAN:INN:JAN];Unipyranamide;Pyrazinoic acid amide;DRG 0124;Aldinamid;Farmizina;Eprazin;pyrazine-2-carboxamide;Tebrazid;Pyrazine carboxylamide;Pyrazine carboxamide;
NamePyrazinamide
CAS98-96-4
SynonymsPyrazinamide (TN);Pirazinamid;Pirazimida;D-50;T 165;Novamid;NCI-C01785;Pyrazineamide;MK 56;2-Carbamylpyrazine;D-50 (VAN);Pirazinamida [INN-Spanish];Pirazinamide [DCIT];PZA;2-Pyrazinecarboxamide;1/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9;Pyrazinamide (JP14/USP);5-25-04-00178 (Beilstein Handbook Reference);Prestwick_811;Zinamide;Pyrazinamidum [INN-Latin];PYZ;Pyrazinecarboxylic acid amide;Aldinamide;Pyrazinamide [BAN:INN:JAN];Unipyranamide;Pyrazinoic acid amide;DRG 0124;Aldinamid;Farmizina;Eprazin;pyrazine-2-carboxamide;Tebrazid;Pyrazine carboxylamide;Pyrazine carboxamide;
EINECS(EC#)202-717-6
Molecular FormulaC5H5N3O
Molecular Weight123.11
Appearanceclear to off-white crystalline powder
storage tempStore in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store below 40C.
Hazard F: Flammable;C: Corrosive;
Risk R11
Safety
Hazard Codes:?
F,?
C?
Risk Statements: 11-34?
R11:Highly flammable.?
R34:Causes burns.
Safety Statements: 22-24/25-45-36/37/39-26-16?
S22:Do not breathe dust.?
S24/25:Avoid contact with skin and eyes.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S16:Keep away from sources of ignition.
WGK Germany: 3
RTECS of Pyrazinamide (CAS NO.98-96-4): UQ2275000
HS Code 29339990
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
1680mg/kg (1680mg/kg) |
? |
Chemotherapia. Vol. 5, Pg. 39, 1962. |
| mouse |
LD50 |
subcutaneous |
2973mg/kg (2973mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 1038, 1995. |
| mouse |
LDLo |
oral |
3gm/kg (3000mg/kg) |
BEHAVIORAL: EXCITEMENT
BEHAVIORAL: ATAXIA |
American Review of Tuberculosis. Vol. 70, Pg. 423, 1954. |
| rat |
LDLo |
oral |
3gm/kg (3000mg/kg) |
BEHAVIORAL: EXCITEMENT
BEHAVIORAL: ATAXIA |
American Review of Tuberculosis. Vol. 70, Pg. 423, 1954. |
| women |
TDLo |
oral |
10mg/kg (10mg/kg) |
VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION |
JAMA, Journal of the American Medical Association. Vol. 127, Pg. 1356, 1997. |
