Butanedioic acid,1-[(2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl]ester, sodium salt (1:1) cas no:982-57-0
Synonyms: Butanedioicacid, mono[(2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl]ester, monosodium salt (9CI);Butanedioic acid,mono[2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] ester,monosodium salt, [R-(R*,R*)]-;Succinic acid, a-monoester with D-threo-(-)-2,2-dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl]acetamide,monosodium salt (8CI);Betamicetin;Chloramphenicol monosuccinate sodium salt;Chloramphenicol succinate sodium;Clorofenicina;Cloromoin;Levomycetin-Nalcein;Mychel-S;Nalecin;Nevimycin;Protophenicol;Sodium chloramphenical monosuccinate;Solnicol;
NameButanedioic acid,1-[(2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl]ester, sodium salt (1:1)
CAS982-57-0
SynonymsButanedioicacid, mono[(2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl]ester, monosodium salt (9CI);Butanedioic acid,mono[2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] ester,monosodium salt, [R-(R*,R*)]-;Succinic acid, a-monoester with D-threo-(-)-2,2-dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl]acetamide,monosodium salt (8CI);Betamicetin;Chloramphenicol monosuccinate sodium salt;Chloramphenicol succinate sodium;Clorofenicina;Cloromoin;Levomycetin-Nalcein;Mychel-S;Nalecin;Nevimycin;Protophenicol;Sodium chloramphenical monosuccinate;Solnicol;
EINECS(EC#)213-568-1
Molecular FormulaC15H16Cl2N2O8.Na
Molecular Weight445.18
AppearanceWhite powder.
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Hazard Xn: Harmful;
Risk R40
Safety
Moderately toxic by intravenous and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cl−, Na2O, and NOx. See also other chloramphenicol entries.
Hazard Codes:
Xn
Risk Statements:
R40:Limited evidence of a carcinogenic effect.
Safety Statements:
S22:Do not breathe dust.
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: AB6905000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| infant |
LDLo |
intravenous |
135mg/kg/3D-I (135mg/kg) |
behavioral: somnolence (general depressed activity) behavioral: irritability lungs, thorax, or respiration: respiratory stimulation
|
Journal of Pediatrics. Vol. 103, Pg. 485, 1983.
|
| mouse |
LD50 |
intravenous |
1530mg/kg (1530mg/kg) |
|
Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972. |
| rat |
LD50 |
intraperitoneal |
1400mg/kg (1400mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 248, 1982. |
| rat |
LD50 |
intravenous |
1500mg/kg (1500mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 248, 1982. |
