Cefpirome sulfate cas no:98753-19-6
Synonyms: Cefrom;(7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-5-yl)-2-methoxyimino-acetyl]amino]-3-(2-azoniabicyclo[4.3.0]nona-2,4,10-trien-2-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; sulfuric acid;5H-1-Pyrindinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-6,7-dihydro-, (6R-(6-alpha,7-beta(Z)))-, sulfate (1:1);5H-1-Pyrindinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-6,7-dihydro-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-, sulfate (1:1);CPR;5H-Cyclopenta[b]pyridinium,1-[[7-[[(2-amino- 4-thiazolyl)(methoxyimino)acetyl]amino]-2- carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct- 2-en-3-yl]methyl]-6,7-dihydro-,[6R-[6R,7a- (Z)]]-,sulfate (1:1);1-(((6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-6,7-dihydro-5H-1-pyrindinium hydroxide, inner salt, 7(sup 2)-(Z)-(O-methyloxime), sulfate (1:1);HR 810 sulfate;Cefpirome sulfate [USAN:JAN];(6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-(2-azoniabicyclo[4.3.0]nona-2,4,10-trien-2-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; sulfuric acid;Cefrom (TN);Cefpirome sulfate (JP14/USAN);Cefpirome Sulphate (Buffered);Cefpirome Sulphate Sterile;Cefpirome;
NameCefpirome sulfate
CAS98753-19-6
SynonymsCefrom;(7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-5-yl)-2-methoxyimino-acetyl]amino]-3-(2-azoniabicyclo[4.3.0]nona-2,4,10-trien-2-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; sulfuric acid;5H-1-Pyrindinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-6,7-dihydro-, (6R-(6-alpha,7-beta(Z)))-, sulfate (1:1);5H-1-Pyrindinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-6,7-dihydro-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-, sulfate (1:1);CPR;5H-Cyclopenta[b]pyridinium,1-[[7-[[(2-amino- 4-thiazolyl)(methoxyimino)acetyl]amino]-2- carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct- 2-en-3-yl]methyl]-6,7-dihydro-,[6R-[6R,7a- (Z)]]-,sulfate (1:1);1-(((6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-6,7-dihydro-5H-1-pyrindinium hydroxide, inner salt, 7(sup 2)-(Z)-(O-methyloxime), sulfate (1:1);HR 810 sulfate;Cefpirome sulfate [USAN:JAN];(6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-(2-azoniabicyclo[4.3.0]nona-2,4,10-trien-2-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; sulfuric acid;Cefrom (TN);Cefpirome sulfate (JP14/USAN);Cefpirome Sulphate (Buffered);Cefpirome Sulphate Sterile;Cefpirome;
Molecular FormulaC22H22N6O5S2.H2SO4
Molecular Weight612.67
AppearanceWhite or off white crystalline powder
storage tempStore at 0-5°C
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| monkey |
LD50 |
intravenous |
1414mg/kg (1414mg/kg) |
? |
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 35, Pg. 2178, 1993. |
| mouse |
LD50 |
intraperitoneal |
3850mg/kg (3850mg/kg) |
? |
Journal of Toxicological Sciences. Vol. 15(Suppl, |
| mouse |
LD50 |
intravenous |
2400mg/kg (2400mg/kg) |
? |
Journal of Toxicological Sciences. Vol. 15(Suppl, |
| mouse |
LD50 |
oral |
16200mg/kg (16200mg/kg) |
? |
Journal of Toxicological Sciences. Vol. 15(Suppl, |
| rabbit |
LDLo |
intravenous |
2gm/kg (2000mg/kg) |
KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION
KIDNEY, URETER, AND BLADDER: CHANGES IN BLADDER WEIGHT |
Journal of Toxicological Sciences. Vol. 15(Suppl, |
| rat |
LD50 |
intraperitoneal |
5800mg/kg (5800mg/kg) |
? |
Journal of Toxicological Sciences. Vol. 15(Suppl, |
| rat |
LD50 |
intravenous |
1900mg/kg (1900mg/kg) |
? |
Journal of Toxicological Sciences. Vol. 15(Suppl, |
| rat |
LD50 |
oral |
> 8gm/kg (8000mg/kg) |
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Journal of Toxicological Sciences. Vol. 15(Suppl, |
| rat |
LD50 |
subcutaneous |
> 10gm/kg (10000mg/kg) |
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Journal of Toxicological Sciences. Vol. 15(Suppl, |
