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2-Amino-4-nitrophenol cas no:99-57-0

Synonyms: 4-Nitro-2-Aminophenol; 4-NAP

Identification
Name2-Amino-4-nitrophenol
CAS99-57-0
Synonyms4-Nitro-2-Aminophenol; 4-NAP
EINECS(EC#)202-767-9
Molecular FormulaC6H6N2O3
Molecular Weight154.12
Chemical Properties
Appearanceorange prisms or yellow powder
refractive index1.688
storage tempStore in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Safety Data

Hazard Xn:Harmful
Risk R36/37/38;R40;R43;R68
Safety

Poison by intraperitoneal route. Moderately toxic by ingestion. An eye irritant. Mutation data reported. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:?IrritantXi,?HarmfulXn
Risk Statements: 36/37/38-68-43-40-20/21/22
R36/37/38: Irritating to eyes, respiratory system and skin.?
R68: Possible risk of irreversible effects.?
R43: May cause sensitization by skin contact.?
R40: Limited evidence of a carcinogenic effect.?
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-45-36/37/39-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S36: Wear suitable protective clothing.
WGK Germany: 2
RTECS: SJ6300000
Hazard Note of 2-Amino-4-nitrophenol (CAS NO.99-57-0): Irritant


Toxicity
1. ???

eye-rbt 100?mg/24H MOD

??? 28ZPAK ?? Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.:?1972,107.
2. ???

mmo-sat 20?μg/plate

??? CMMUAO ?? Chemical Mutagens. Principles and Methods for Their Detection 8 (1983),151.
3. ???

mma-sat 100?μg/plate

??? PNASA6 ?? Proceedings of the National Academy of Sciences of the United States of America. 72 (1975),2423.
4. ???

pic-esc 100?mmol/L

??? MDMIAZ ?? Medycyna Doswiadczalna i Mikrobiologia. 31 (1979),11.
5. ???

orl-rat TDLo:13,750?mg/kg/15D-I:REP,CAR

??? NTPTR* ?? National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-339 ,1988.
6. ???

orl-rat LD50:2400?mg/kg

??? FCTXAV ?? Food and Cosmetics Toxicology. 15 (1977),607.
7. ???

ipr-rat LD50:246?mg/kg

??? JTEHD6 ?? Journal of Toxicology and Environmental Health. 2 (1977),657.
8. ???

orl-mus LD50:850?mg/kg

??? GTPZAB ?? Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 25 (8)(1981),50.
9. ???

ipr-mus LD50:143?mg/kg

??? GENEA3 ?? Genetica (The Hague). 26 (1985),109.

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