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N,N-Dimethylphenylenediamine cas no:99-98-9

Synonyms: 4-ANIMODIMETHYLANILINE; 4-AMINODIMETHYLANILINE; 4-AMINO-N,N-DIMETHYLANILINE; 4-DIMETHYLAMINOANILINE; Dimethyl-p-phenylenediamine; DIMETHYL(N,N-)-P-PHENYLENEDIAMINE; WURSTER'S RED; 4-(dimethylamino)benzenamine

Identification
NameN,N-Dimethylphenylenediamine
CAS99-98-9
Synonyms4-ANIMODIMETHYLANILINE; 4-AMINODIMETHYLANILINE; 4-AMINO-N,N-DIMETHYLANILINE; 4-DIMETHYLAMINOANILINE; Dimethyl-p-phenylenediamine; DIMETHYL(N,N-)-P-PHENYLENEDIAMINE; WURSTER'S RED; 4-(dimethylamino)benzenamine
EINECS(EC#)202-807-5
Molecular FormulaC8H12N2
Molecular Weight136.2
Chemical Properties
AppearanceLight brown solid or liquid
refractive index1.626
storage temp2-8°C
Sensitive Light Sensitive
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard T:Toxic;
Risk R23/24/25;R36/37/38
Safety

Hazard Codes: ToxicT
Risk Statements: 23/24/25-36/37/38 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 28-45-36/37/39-26 
S28:After contact with skin, wash immediately with plenty of soap-suds. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: ST0874000
F: 8-10-23
Hazard Note: Toxic/Keep Cold
HazardClass: 6.1
PackingGroup: II
Hazardous Substances Data: 99-98-9(Hazardous Substances Data)


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo oral 20mg/kg (20mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
dog LDLo intraperitoneal 10mg/kg (10mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 262, 1949.
dog LDLo intravenous 51mg/kg (51mg/kg)   Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
dog LDLo skin 84mg/kg (84mg/kg)   Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
guinea pig LCLo inhalation 240ppb (0.24ppm) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: EXCITEMENT
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
guinea pig LD50 intraperitoneal 45mg/kg (45mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 262, 1949.
guinea pig LD50 skin 500uL/kg (0.5mL/kg)   National Technical Information Service. Vol. OTS0555326,
guinea pig LDLo subcutaneous 100mg/kg (100mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
human TDLo skin 14ug/kg (0.014mg/kg) BLOOD: HEMORRHAGE

SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE

SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER TOPICAL EXPOSURE"
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
mouse LD50 intraperitoneal 25mg/kg (25mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 262, 1949.
mouse LD50 oral 30mg/kg (30mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
National Technical Information Service. Vol. OTS0555326,
rabbit LCLo inhalation 500ppb (0.5ppm) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: EXCITEMENT
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rabbit LD50 intraperitoneal 100mg/kg (100mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 262, 1949.
rabbit LDLo oral 150mg/kg (150mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: COMA
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rabbit LDLo skin 60mg/kg (60mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rabbit LDLo subcutaneous 60mg/kg (60mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: COMA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rat LD50 intraperitoneal 21mg/kg (21mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 262, 1949.
rat LD50 oral 50mg/kg (50mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
National Technical Information Service. Vol. OTS0555326,
rat LDLo subcutaneous 50mg/kg (50mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: COMA
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.

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