Levodropropizine cas no:99291-25-5
Synonyms: (-)-Dropropizine;1,2-Propanediol,3-(4-phenyl-1-piperazinyl)-,(2S)-;DF 526;Levodropropizina [INN-Spanish];Levodropropizine [INN];1,2-Propanediol, 3-(4-phenylpiperazin-1-yl)-, S(-)-;Levodropropizinum [INN-Latin];Levotuss;Danka;(2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol;(-)-(S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol;S(-)-3-(4-Phenylpiperazin-1-yl)propane-1,2-diol;1,2-Propanediol, 3-(4-phenylpiperazin-1-yl)-, S(-)-;S(-)-3-(4-Phenylpiperazin-1-yl)propane-1,2-diol;
NameLevodropropizine
CAS99291-25-5
Synonyms(-)-Dropropizine;1,2-Propanediol,3-(4-phenyl-1-piperazinyl)-,(2S)-;DF 526;Levodropropizina [INN-Spanish];Levodropropizine [INN];1,2-Propanediol, 3-(4-phenylpiperazin-1-yl)-, S(-)-;Levodropropizinum [INN-Latin];Levotuss;Danka;(2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol;(-)-(S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol;S(-)-3-(4-Phenylpiperazin-1-yl)propane-1,2-diol;1,2-Propanediol, 3-(4-phenylpiperazin-1-yl)-, S(-)-;S(-)-3-(4-Phenylpiperazin-1-yl)propane-1,2-diol;
Molecular FormulaC13H20N2O2
Molecular Weight236.3101
AppearanceWhite crystalling power
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TZ1075100
- CHEMICAL NAME :
- 1,2-Propanediol, 3-(4-phenylpiperazin-1-yl)-, S(-)-
- CAS REGISTRY NUMBER :
- 99291-25-5
- LAST UPDATED :
- 199609
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C13-H20-N2-O2
- MOLECULAR WEIGHT :
- 236.35
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 887 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Gastrointestinal - other changes
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 38,1150,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 401 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 38,1150,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1281 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Gastrointestinal - other changes
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 38,1150,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 408 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 38,1150,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 2493 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Gastrointestinal - other changes
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 38,1150,1988
