Ampiroxicam cas no:99464-64-9
Synonyms: ethyl 1-[[9-methyl-10,10-dioxo-8-(pyridin-2-ylcarbamoyl)-10$l^{6}-thia-9-azabicyclo[4.4.0]deca-1,3,5,7-tetraen-7-yl]oxy]ethyl carbonate;Ampiroxicamum [Latin];Flucam (TN);Flucam;(+-)-4-(1-Hydroxyethoxy)-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide ethyl carbonate (ester), 1,1-dioxide;Ampiroxicam (+-);Ampiroxicam (JAN);Carbonic acid, ethyl 1-((2-methyl-3-((2-pyridinylamino)carbonyl)-2H-1,2-benzothiazin-4-yl)oxy)ethyl ester, S,S-dioxide;Ampiroxicam [BAN:INN:JAN];Carbonic acid,esters,ethyl 1-[[2-methyl-1,1-dioxido-3-[(2- pyridinylamino)carbonyl]-2H-1,2- benzothiazin-4-yl]oxy]ethyl ester;CP 65703;Ampiroxicam 99%;Ampiroxicamum;
NameAmpiroxicam
CAS99464-64-9
Synonymsethyl 1-[[9-methyl-10,10-dioxo-8-(pyridin-2-ylcarbamoyl)-10$l^{6}-thia-9-azabicyclo[4.4.0]deca-1,3,5,7-tetraen-7-yl]oxy]ethyl carbonate;Ampiroxicamum [Latin];Flucam (TN);Flucam;(+-)-4-(1-Hydroxyethoxy)-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide ethyl carbonate (ester), 1,1-dioxide;Ampiroxicam (+-);Ampiroxicam (JAN);Carbonic acid, ethyl 1-((2-methyl-3-((2-pyridinylamino)carbonyl)-2H-1,2-benzothiazin-4-yl)oxy)ethyl ester, S,S-dioxide;Ampiroxicam [BAN:INN:JAN];Carbonic acid,esters,ethyl 1-[[2-methyl-1,1-dioxido-3-[(2- pyridinylamino)carbonyl]-2H-1,2- benzothiazin-4-yl]oxy]ethyl ester;CP 65703;Ampiroxicam 99%;Ampiroxicamum;
EINECS(EC#)安全数据
Molecular FormulaC20H21N3O7S
Molecular Weight447.46
AppearancePowder
refractive index1.629
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| monkey |
LD50 |
oral |
> 500mg/kg (500mg/kg) |
? |
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 36, Pg. 432, 1994. |
| mouse |
LD50 |
intraperitoneal |
1358mg/kg (1358mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 119, 1995. |
| mouse |
LD50 |
oral |
2291mg/kg (2291mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 119, 1995. |
| mouse |
LD50 |
subcutaneous |
4259mg/kg (4259mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 119, 1995. |
| rat |
LD50 |
intraperitoneal |
282mg/kg (282mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 119, 1995. |
| rat |
LD50 |
oral |
747mg/kg (747mg/kg) |
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
KIDNEY, URETER, AND BLADDER: INCONTINENCE |
Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 1, 1992. |
| rat |
LD50 |
subcutaneous |
2598mg/kg (2598mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 119, 1995. |
