999-97-3|1,1,1,3,3,3-HexamethyldisilazaneProducts Supply

1,1,1,3,3,3-Hexamethyldisilazane cas no:999-97-3

Synonyms: HMDS; Hexamethyldisilazane; DYNASYLAN HMDS; Bis(trimethylsilyl)amine; 1,1,1,3,3,3,-HEXAMETHYLDISILA-

Identification

Name1,1,1,3,3,3-Hexamethyldisilazane
CAS999-97-3
SynonymsHMDS; Hexamethyldisilazane; DYNASYLAN HMDS; Bis(trimethylsilyl)amine; 1,1,1,3,3,3,-HEXAMETHYLDISILA-
EINECS(EC#)213-668-5
Molecular FormulaC6H19NSi2
Molecular Weight161.39

Chemical Properties

AppearanceClear liquid
refractive index1.4069-1.4089
storage temp2-8°C
Sensitive Moisture Sensitive

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass3

Safety Data

Hazard C:Corrosive
Risk R11;R20/21/22;R34
Safety

Moderately toxic by ingestion and intraperitoneal routes. Questionable carcinogen with experimental tumorigenic data. A dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: ?F,? C,? Xn
The Risk Statements information of? Hexamethyldisilazane (CAS NO.999-97-3):
11:? Highly Flammable?
34:? Causes burns?
20/21/22:? Harmful by inhalation, in contact with skin and if swallowed?
The Safety Statements information of? Hexamethyldisilazane (CAS NO.999-97-3):
16:? Keep away from sources of ignition - No smoking?
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
45:? In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)?
36/37/39:? Wear suitable protective clothing, gloves and eye/face protection?
RIDADR: UN 3286 3/PG 2
WGK Germany: 2
RTECS: JM9230000
F: 21
Hazard Note: Flammable
TSCA: Yes
HazardClass: 3
PackingGroup: II

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	skin	1mL/kg (1mL/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: MUSCLE WEAKNESS SKIN AND APPENDAGES (SKIN): HAIR: OTHER	National Technical Information Service. Vol. OTS0537734,
mouse	LC50	inhalation	12gm/m3/2H (12000mg/m3)	BEHAVIORAL: GENERAL ANESTHETIC CARDIAC: PULSE RATE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986.
mouse	LD50	intravenous	> 100mg/kg (100mg/kg)	?	Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,
mouse	LD50	oral	850mg/kg (850mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC CARDIAC: PULSE RATE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986.
mouse	LDLo	intraperitoneal	650mg/kg (650mg/kg)	IMMUNOLOGICAL INCLUDING ALLERGIC: DECREASED IMMUNE RESPONSE	Personal Communication from G.D. Stoner, Dept. of Community Medicine, School of Medicine, Univ. of California, La Jolla, CA 92037, May 25, 1975Vol. 27MAY1975,
rabbit	LD50	oral	1100mg/kg (1100mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION CARDIAC: PULSE RATE	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986.
rabbit	LD50	skin	710uL/kg (0.71mL/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 12, Pg. 576, 1993.
rat	LC50	inhalation	8700mg/m3/4H (8700mg/m3)	BEHAVIORAL: GENERAL ANESTHETIC CARDIAC: PULSE RATE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986.
rat	LD50	intraperitoneal	800mg/kg (800mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: MUSCLE WEAKNESS SKIN AND APPENDAGES (SKIN): HAIR: OTHER	National Technical Information Service. Vol. OTS0537734,
rat	LD50	oral	850mg/kg (850mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC CARDIAC: PULSE RATE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986.

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Depew Fine Chemical Co.,Ltd.: Tel:+86-571-87630650, 87630656, 87630657; Address: Room 202,No.317 Wantang Road,Hangzhou,China

Shanghai BioTio Co., Ltd.: Tel:; Address: 5 th Floor, Modern Communication Building , Golden Bridge E. P. Z. ,No. 201, New Jinqiao Road. Shanghai P.R. of China

Zhejiang HuTu PharmChem Co., Ltd.: Tel:+86-570-6121003 +86-570-6121498; Address: 2 Yuanyi Road, Kaihua Industrial Park, Zhejiang, China

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Guan Enkang Chemical Co ., Ltd.: Tel:+86-(316)-6126555; Address: Dashafa, Niutuo Town, Guan, Langfang, Hebei 065501,

Shanghai Lonyung Industry Ltd.: Tel:+86-(21)-5079-0537; Address: Jing Yong Yi industrial base 7th,Cang Jing Road 398, Songjiang Hi-Tech Park, Songjiang District, Shanghai,

1,1,1,3,3,3-Hexamethyldisilazane cas no:999-97-3

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