10457-90-6|BromoperidolProducts Supply - Chemical intermediates Network

Bromoperidol cas no:10457-90-6

Synonyms: Butyrophenone,4-[4-(p-bromophenyl)-4-hydroxypiperidino]-4'-fluoro- (8CI);4-[4-(4-Bromophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone;Azurene;4-[4-(4-Bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one;

Identification

NameBromoperidol
CAS10457-90-6
SynonymsButyrophenone,4-[4-(p-bromophenyl)-4-hydroxypiperidino]-4'-fluoro- (8CI);4-[4-(4-Bromophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone;Azurene;4-[4-(4-Bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one;
EINECS(EC#)233-943-3
Molecular FormulaC₂₁H₂₃BrFNO₂
Molecular Weight420.36

Chemical Properties

AppearanceTan solid
refractive index1.59
storage tempRefrigerator

Safety Data

Hazard Xn
Risk 22
Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of F⁻, Br⁻ and NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	156mg/kg (156mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 1461, 1985.
mouse	LD50	intravenous	18900ug/kg (18.9mg/kg)	sense organs and special senses: ptosis: eye behavioral: tremor behavioral: somnolence (general depressed activity)	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 45, 1974.
mouse	LD50	oral	174mg/kg (174mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 1461, 1985.
mouse	LD50	subcutaneous	114mg/kg (114mg/kg)	sense organs and special senses: ptosis: eye behavioral: somnolence (general depressed activity) behavioral: tremor	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 45, 1974.
rat	LD50	intraperitoneal	323mg/kg (323mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 1461, 1985.
rat	LD50	intravenous	10mg/kg (10mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 16, Pg. 1461, 1985.
rat	LD50	oral	359mg/kg (359mg/kg)	sense organs and special senses: ptosis: eye behavioral: somnolence (general depressed activity) behavioral: tremor	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 45, 1974.
rat	LD50	subcutaneous	84mg/kg (84mg/kg)	sense organs and special senses: ptosis: eye behavioral: somnolence (general depressed activity) behavioral: tremor	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 45, 1974.

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Bromoperidol cas no:10457-90-6

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