Manus Aktteva

We undertake to serve the industry in almost all spheres by facilitating the sourcing of required Pharmaceutical raw materials to various advance level intermediates and molecules in the field of Pharmaceuticals, Nutraceuticals, Specialty Chemicals and Biotechnology.

Aliskiren Hemifumarate Intermediates
Our Aliskiren is a first in class non peptide potent renin inhibitor which is approved by the U.S. Food and Drug Administration for the treatment of hypertension. We provide Aliskiren Hemifumarate Intermediates that include 3-isovaleroyl-4(R)-benzyl-oxazolidin-2one, 3-isovaleroyl-4(S)-benzyl-oxazolidin-2one, 3-Amino-2,2-dimethylpropionamide and 3-Hydroxy-4-methoxybenzylalcohol.

Bortezomib
Our Bortezomib is the first therapeutic proteasome inhibitor to be tested in humans. It is approved in the U.S. for treating relapsed multiple myeloma and mantle cell lymphoma. We also offer Bortezomib, 179324-69-7, for RND requirements, along with its intermediates for evaluation, pilots and commercial requirements with supportive technical package required for evaluation for intermediates. Our Bortezomib Intermediates include (R)-BoroLeu-(+)-Pinanediol-CF3COOH, and N-[(1S)-1-benzyl-2-({(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}amino)-2-oxoethyl]-2-pyrazinecarboxamide.

Dasatinib Monohydrate
Our Dasatinib, is a drug approved for use in patients with chronic myelogenous leukemia after imatinib treatment and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). We offer Dasatinib Monohydrate, 863127-77-9, for RND quantities, along with its intermediates for evaluation, pilots and commercial requirements with supportive technical package required for evaluation for intermediates. We also Dasatinib Monohydrate Intermediates such as 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide, Ethyl 2-amino 5-thiazolecarboxylate and Methyl 2-amino 5-thiazolecarboxylate.

Dronedarone Hydrochloride
We specialize in Dronedarone Hydrochloride Intermediates that include N-(3-Chloropropyl)dibutylamine, 1-Dibutylamino-3-chloropropane hydrochloride, 2-butyl-5-(methylsulphonamide)benzofuran, and 2-butyl-5-(acetamide)benzofuran.

erlotinib hydrochloride Intermediates

• 6,7-bis-(2-methoxyethoxy)-4(3h)-quinazolinone
• 4-Chloro-6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazoline
• 3-Aminophenylacetylene

Ertapenem Sodium Intermediates
We offer Ertapenem Intermediate, also known as Ertapenem Side chain, 3-[(2S,4S)-4-Mercaptopyrrolidine-2-carboxamido]benzoic acid hydrochloride, 219909-83-8, for the requirements of RND, evaluation, pilots and commercial along with supportive technical package required for evaluation for intermediates. Ertapenem is a carbapenem antibiotic structurally very similar to meropenem which possess a 1-?-methyl group.

Escitalopram Oxalate
We provide Escitalopram Intermediate and Ezetimibe Intermediates for the evaluation, pilots and commercial requirements with supportive technical package required for evaluation.

Lacosamide Intermediates
Our Lacosamide Intermediates include

• BOC-D-Serine, Boc-D-Ser-OH
• Boc-O-Methyl-D-Ser
• Cbz-O-Methyl-D-Ser
• (R)-2-Amino-3-methoxypropanoic acid hydrochloride

Lapatinib Ditosylate Intermediates
Lapatinib ditosylate is an anti-cancer drug used for treatment for solid tumours such as breast and lung cancer. Our Lapatinib Ditosylate Intermediates include 3-Chloro-4-(3-fluoro-benzyloxy)-phenylamine, 2-Chloro-1-(3-fluoro-benzyloxy)-4-nitro-benzene and 2-Aminoethylmethylsulfone hydrochloride.

Imatinib Mesylate
Imatinib is a drug used to treat certain types of cancer. It is currently marketed as its mesylate salt, imatinib mesylate. It is used in treating chronic myelogenous leukemia, gastrointestinal stromal tumors and a number of other malignancies. It is the first member of a new class of agents that act by inhibiting particular tyrosine kinase enzymes, instead of non-specifically inhibiting rapidly dividing cells.

Paclitaxel
Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is also used for the prevention of restenosis. Paclitaxel works by interfering with normal microtubule growth during cell division. Together with docetaxel, it forms the drug category of the taxanes.

Sermorelin
Sermorelin is a growth hormone releasing hormone analogue. It is a 29-amino acid polypeptide representing the 1-29 fragments from endogenous human growth hormone releasing hormone, and is thought to be the shortest fully functional fragment of GHRH. It is used as a test for growth hormone secretion. We offer Sermorelin, 86168-78-7, for RND and its crude form.

Yohimbine Hydrochloride
We offer Yohimbine Hydrochloride, 65-19-0, USP, for evaluation, pilots and commercial requirements with supportive technical package required for evaluation. Our Yohimbine hcl is the standardized form of yohimbine.

We undertake to serve the industry in almost all spheres by facilitating the sourcing of required Pharmaceutical raw materials to various advance level intermediates and molecules in the field of Pharmaceuticals, Nutraceuticals, Specialty Chemicals and Biotechnology. We are serving major pharmaceutical companies to R&D facilities, small facilities to remotely placed facilities and institutions? efficiently and promptly across the globe.

Manus Aktteva has associated with MNC?S, Pharma majors and of course medium sized and small formulation companies.