106941-25-7|AdefovirProducts Supply - Chemical intermediates Network

Adefovir cas no:106941-25-7

Synonyms: ((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid;9-(2-Phosphorylmethoxyethyl)adenine;PMEA;Adefovir [USAN:INN];2-(6-aminopurin-9-yl)ethoxymethylphosphonic acid;N-(2-Phophonomethoxyethyl-2,6-diaminopurine);GS 0393;GS 393;9-(2-(Phosphonomethoxy)ethyl)adenine;Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)-;9-[2-Phosphonylmethoxyethyl]adenine;9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA);9-[2-phosphonyl methoxyethyl]adenine;Adefovir dipivox;9-[2-(phosphonomethoxy)ethyl]adenine;[[2-(6-amino-9H-purin-9-yl) ethoxy] methyl] phosphonic acid;9-(2-phosphonyl methoxyethyl)adenine;Adefovir Dipivozil;9-(2-Phosphonylmethoxyethyl)adenine;

Identification

NameAdefovir
CAS106941-25-7
Synonyms((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid;9-(2-Phosphorylmethoxyethyl)adenine;PMEA;Adefovir [USAN:INN];2-(6-aminopurin-9-yl)ethoxymethylphosphonic acid;N-(2-Phophonomethoxyethyl-2,6-diaminopurine);GS 0393;GS 393;9-(2-(Phosphonomethoxy)ethyl)adenine;Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)-;9-[2-Phosphonylmethoxyethyl]adenine;9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA);9-[2-phosphonyl methoxyethyl]adenine;Adefovir dipivox;9-[2-(phosphonomethoxy)ethyl]adenine;[[2-(6-amino-9H-purin-9-yl) ethoxy] methyl] phosphonic acid;9-(2-phosphonyl methoxyethyl)adenine;Adefovir Dipivozil;9-(2-Phosphonylmethoxyethyl)adenine;
Molecular FormulaC₈H₁₂N₅O₄P
Molecular Weight273.19

Chemical Properties

Appearancewhite to off-white powder

Safety Data

Safety

Mutation data reported. When heated to decomposition it emits toxic vapors of NO_x and PO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD	intravenous	> 1gm/kg (1000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Antimicrobial Agents and Chemotherapy. Vol. 40, Pg. 1072, 1996.
mouse	LDLo	intraperitoneal	1600mg/kg (1600mg/kg)	?	Antimicrobial Agents and Chemotherapy. Vol. 40, Pg. 1072, 1996.

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Changzhou Leo Chemical Co.,Ltd.: Tel:; Address: NO. 538 XINQING ROAD, XINZHA TOWN, ZHONGLOU DISTRICT, CHANGZHOU, JIANGSU, CHINA

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AOKChem Co., Ltd.: Tel:+86-(21)-50791030 / 68712331; Address: Room 203, Block D, No.333 Cailun Road, Zhangjiang High-tech Park, Shanghai 201203,

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Watson International Ltd.: Tel:+86-(512)-55117610; Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332,

Star Lake Bioscience Co., Inc.: Tel:+86-(758)-2290060/61/68; Address: No.67, Gongnong Road North, Zhaoqing, Guangdong 526060,

Manus Aktteva: Tel:+91-(79)-65123395; Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006,

China Langchem Inc.: Tel:+86-(21)-58956006; Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203,

Adefovir cas no:106941-25-7

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