106941-25-7|AdefovirProducts Supply - Chemical intermediates Network

Adefovir cas no:106941-25-7

Synonyms: ((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid;9-(2-Phosphorylmethoxyethyl)adenine;PMEA;Adefovir [USAN:INN];2-(6-aminopurin-9-yl)ethoxymethylphosphonic acid;N-(2-Phophonomethoxyethyl-2,6-diaminopurine);GS 0393;GS 393;9-(2-(Phosphonomethoxy)ethyl)adenine;Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)-;9-[2-Phosphonylmethoxyethyl]adenine;9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA);9-[2-phosphonyl methoxyethyl]adenine;Adefovir dipivox;9-[2-(phosphonomethoxy)ethyl]adenine;[[2-(6-amino-9H-purin-9-yl) ethoxy] methyl] phosphonic acid;9-(2-phosphonyl methoxyethyl)adenine;Adefovir Dipivozil;9-(2-Phosphonylmethoxyethyl)adenine;

Identification

NameAdefovir
CAS106941-25-7
Synonyms((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid;9-(2-Phosphorylmethoxyethyl)adenine;PMEA;Adefovir [USAN:INN];2-(6-aminopurin-9-yl)ethoxymethylphosphonic acid;N-(2-Phophonomethoxyethyl-2,6-diaminopurine);GS 0393;GS 393;9-(2-(Phosphonomethoxy)ethyl)adenine;Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)-;9-[2-Phosphonylmethoxyethyl]adenine;9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA);9-[2-phosphonyl methoxyethyl]adenine;Adefovir dipivox;9-[2-(phosphonomethoxy)ethyl]adenine;[[2-(6-amino-9H-purin-9-yl) ethoxy] methyl] phosphonic acid;9-(2-phosphonyl methoxyethyl)adenine;Adefovir Dipivozil;9-(2-Phosphonylmethoxyethyl)adenine;
Molecular FormulaC₈H₁₂N₅O₄P
Molecular Weight273.19

Chemical Properties

Appearancewhite to off-white powder

Safety Data

Safety

Mutation data reported. When heated to decomposition it emits toxic vapors of NO_x and PO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD	intravenous	> 1gm/kg (1000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Antimicrobial Agents and Chemotherapy. Vol. 40, Pg. 1072, 1996.
mouse	LDLo	intraperitoneal	1600mg/kg (1600mg/kg)	?	Antimicrobial Agents and Chemotherapy. Vol. 40, Pg. 1072, 1996.

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Adefovir cas no:106941-25-7

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