106941-25-7|AdefovirProducts Supply - Chemical intermediates Network

Adefovir cas no:106941-25-7

Synonyms: ((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid;9-(2-Phosphorylmethoxyethyl)adenine;PMEA;Adefovir [USAN:INN];2-(6-aminopurin-9-yl)ethoxymethylphosphonic acid;N-(2-Phophonomethoxyethyl-2,6-diaminopurine);GS 0393;GS 393;9-(2-(Phosphonomethoxy)ethyl)adenine;Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)-;9-[2-Phosphonylmethoxyethyl]adenine;9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA);9-[2-phosphonyl methoxyethyl]adenine;Adefovir dipivox;9-[2-(phosphonomethoxy)ethyl]adenine;[[2-(6-amino-9H-purin-9-yl) ethoxy] methyl] phosphonic acid;9-(2-phosphonyl methoxyethyl)adenine;Adefovir Dipivozil;9-(2-Phosphonylmethoxyethyl)adenine;

Identification

NameAdefovir
CAS106941-25-7
Synonyms((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid;9-(2-Phosphorylmethoxyethyl)adenine;PMEA;Adefovir [USAN:INN];2-(6-aminopurin-9-yl)ethoxymethylphosphonic acid;N-(2-Phophonomethoxyethyl-2,6-diaminopurine);GS 0393;GS 393;9-(2-(Phosphonomethoxy)ethyl)adenine;Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)-;9-[2-Phosphonylmethoxyethyl]adenine;9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA);9-[2-phosphonyl methoxyethyl]adenine;Adefovir dipivox;9-[2-(phosphonomethoxy)ethyl]adenine;[[2-(6-amino-9H-purin-9-yl) ethoxy] methyl] phosphonic acid;9-(2-phosphonyl methoxyethyl)adenine;Adefovir Dipivozil;9-(2-Phosphonylmethoxyethyl)adenine;
Molecular FormulaC₈H₁₂N₅O₄P
Molecular Weight273.19

Chemical Properties

Appearancewhite to off-white powder

Safety Data

Safety

Mutation data reported. When heated to decomposition it emits toxic vapors of NO_x and PO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD	intravenous	> 1gm/kg (1000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Antimicrobial Agents and Chemotherapy. Vol. 40, Pg. 1072, 1996.
mouse	LDLo	intraperitoneal	1600mg/kg (1600mg/kg)	?	Antimicrobial Agents and Chemotherapy. Vol. 40, Pg. 1072, 1996.

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Changzhou Xixialong International Trade Co.,ltd.: Tel:; Address: Room 5002, Modern city,Huangshanlu, Xinbei district, Changzhou, China

Beijing Lunarsun Pharmaceutical Co.Ltd.: Tel:086-10-81760039 80771377 80771378 80771379 81760170 81760171 81760172; Address: C1-802, Yangguangguangchang, Anli Road No.68 ,Chaoyang District , 100101 , Beijing , P.R.China

Shanghai Richem International Co., Ltd: Tel:+86-21-31263688; Address: Room 603, Golden Eagle Mansion A, No.1518 Minsheng Road,Pudong, Shanghai (200135), P.R.China

Taizhou Xingming Pharmaceutical Co., Ltd.: Tel:+86-(576)-8516108, 8582618; Address: No. 89, Binhai Road, Jiaojiang, Taizhou, Zhejiang 318000,

Triomphe Fine Chemistry Co., Ltd.: Tel:+86-(21)-65127018; Address: Shanghai Songjiang Industrial Park, Shanghai 200080,

Dalian Wista Pharmaceutical Co., Ltd.: Tel:86-10-84925499; Address: 3rd Floor, Huaguang Building, Courtyard 3, Beiyuan Road, Chaoyang District, Beijing 100012,

ChengDu KaiXinTianRui Technology Development Co., Ltd: Tel:+86-(28)-66490664; Address: 15-1-401 111# BeiShuang Road, ChengDu, Sichuan 610091,

Conier Chem & Pharma Co.,Ltd.: Tel:+86-(23)-62922305; Address: 24 South Section 1, Yihuan Road, Chengdu, Sichuan 610065,

AOKChem Co., Ltd.: Tel:+86-(21)-50791030 / 68712331; Address: Room 203, Block D, No.333 Cailun Road, Zhangjiang High-tech Park, Shanghai 201203,

Ji'nan Zhongke Yitong Chemical Co.,Ltd.: Tel:+86-(531)-8865-8009; Address: No.106 Industry South Road, Jinan, Shandong 250100,

Beijing Lianben Pharm-Chemicals Tech. Co., Ltd.: Tel:+86-(10)-8338-6766; Address: No 406 Xinzhuang, Changxindian, Fengtai District, Beijing 100074,

Taizhou Shanyu Chemical Co., Ltd.: Tel:+86-(576)-88312577; Address: Sanshan,Jiaojiang, Taizhou, Zhejiang,

Taizhou Xingcheng Chempharm Co., Ltd.: Tel:+86-(576)-88886292, 88525005; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road, Taizhou, Zhejiang 318000,

Beijing FortuneStar Science & Technology Development Co., Ltd.: Tel:+86-10-89126510; Address: Zhuyuan 2-2-201, Mingliuhuayuan, Beiqijia, Changping Dist., Beijing 102209, China

Daqing New Century Fine Chemical Co., Ltd.: Tel:0519-6330101; Address: No.39 Jinxingcun, Honggang District, Daqing, Heilongjiang, China

Adefovir cas no:106941-25-7

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