1-Propanamine,3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (3Z)- cas no:113-59-7
Synonyms: 1-Propanamine,3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (Z)-;Thioxanthene-D9,g-propylamine, 2-chloro-N,N-dimethyl-, (Z)-(6CI,7CI,8CI);CPT;CPX;Chlorprothixene;Chlorprotixen;Chlorprotixene;Chlothixen;Iaractan;MK 184;Paxyl;Ro 4-0403;Tactaran;Taractan;Tarasan;Traquilan;Trictal;Truxil;Vetacalm;cis-Chlorprothixene;(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine;(Z)-2-Chloro-9-(3'-dimethylaminopropylidene)thioxanthene;(Z)-2-Chloro-N,N-dimethylthioxanthene-D9,g-propylamine;1-Propanamine, 3- (2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (Z)-;1-propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (3Z)-;Chlorprothixene;Tarasan;Taractan;
Name1-Propanamine,3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (3Z)-
CAS113-59-7
Synonyms1-Propanamine,3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (Z)-;Thioxanthene-D9,g-propylamine, 2-chloro-N,N-dimethyl-, (Z)-(6CI,7CI,8CI);CPT;CPX;Chlorprothixene;Chlorprotixen;Chlorprotixene;Chlothixen;Iaractan;MK 184;Paxyl;Ro 4-0403;Tactaran;Taractan;Tarasan;Traquilan;Trictal;Truxil;Vetacalm;cis-Chlorprothixene;(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine;(Z)-2-Chloro-9-(3'-dimethylaminopropylidene)thioxanthene;(Z)-2-Chloro-N,N-dimethylthioxanthene-D9,g-propylamine;1-Propanamine, 3- (2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (Z)-;1-propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (3Z)-;Chlorprothixene;Tarasan;Taractan;
EINECS(EC#)204-032-8
Molecular FormulaC18H18ClNS
Molecular Weight315.86
Safety Poison by ingestion, intravenous, and intraperitoneal routes. Human reproductive effects by ingestion: impotence. Incompatible with acids; alkalies. When heated to decomposition it emits toxic fumes of Cl−, SOx, and NOx.
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Organism
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Test Type
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Route
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Reported Dose (Normalized Dose)
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Effect
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Source
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man
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LDLo
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oral
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7mg/kg (7mg/kg)
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behavioral: general anesthetic
behavioral: changes in motor activity (specific assay)
behavioral: muscle weakness
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Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 596, 1964.
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mouse
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LD50
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intraperitoneal
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56200ug/kg (56.2mg/kg)
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Cancer Research. Vol. 47, Pg. 5944, 1987.
|
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mouse
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LD50
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intravenous
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36mg/kg (36mg/kg)
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Drugs in Japan Vol. -, Pg. 373, 1990.
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mouse
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LD50
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oral
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50100ug/kg (50.1mg/kg)
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Cancer Research. Vol. 47, Pg. 5944, 1987.
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rabbit
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LD50
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oral
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182mg/kg (182mg/kg)
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"Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 33, 1969.
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rat
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LD50
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oral
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200mg/kg (200mg/kg)
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Drugs in Japan Vol. 6, Pg. 252, 1982.
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