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9(10H)-Anthracenone,1,8-dihydroxy- cas no:1143-38-0

Synonyms: Anthrone,1,8-dihydroxy- (6CI,7CI,8CI);1,8-Dihydroxy-9-anthrone;1,8-Dihydroxyanthrone;Anthra-Derm;Batidrol;Batridol;Chrysodermol;Cignolin;Cigthranol;Derobin;Dithranol;DrithoCreme;Drithoscalp;Lasan;NSC 43970;NSC 629313;Psodadrate;Psoriacid-Stift;Psoriacide;

Identification
Name9(10H)-Anthracenone,1,8-dihydroxy-
CAS1143-38-0
SynonymsAnthrone,1,8-dihydroxy- (6CI,7CI,8CI);1,8-Dihydroxy-9-anthrone;1,8-Dihydroxyanthrone;Anthra-Derm;Batidrol;Batridol;Chrysodermol;Cignolin;Cigthranol;Derobin;Dithranol;DrithoCreme;Drithoscalp;Lasan;NSC 43970;NSC 629313;Psodadrate;Psoriacid-Stift;Psoriacide;
EINECS(EC#)214-538-0
Molecular FormulaC14H10O3
Molecular Weight226.23
Chemical Properties
Appearanceyellow crystalline solid
refractive index1.837
storage temp2-8°C
Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

A mild skin irritant. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard Codes:
Xi: Irritant
T: Toxic
Risk Statements about 1,8-Dihydroxy-anthrone (1143-38-0):
R45 May cause cancer.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about 1,8-Dihydroxy-anthrone (1143-38-0):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53 Avoid exposure - obtain special instructions before use.


Toxicity
1.    

skn-hmn 0.1%/20M MLD

    ADVEA4    Acta Dermato-Venereologica. 67 (1987),72.
2.    

skn-hmn 0.05%/12H

    ADVEA4    Acta Dermato-Venereologica. 18 (1988),117.
3.    

skn-hmn 0.1%/1H MLD

    ADVEA4    Acta Dermato-Venereologica. 67 (1987),72.
4.    

skn-hmn 0.0025%/24H MLD

    ADVEA4    Acta Dermato-Venereologica. 63 (1983),513.
5.    

skn-hmn 0.01%/24H open

    ADVEA4    Acta Dermato-Venereologica. 173 (1986),288.
6.    

skn-hmn 0.02%/48H MOD

    ADVEA4    Acta Dermato-Venereologica. 93 (1989),695.

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