Diclofenamide cas no:120-97-8
Synonyms: m-Benzenedisulfonamide,4,5-dichloro- (6CI,7CI,8CI);1,3-Disulfamoyl-4,5-dichlorobenzene;1,3-Disulfamyl-4,5-dichlorobenzene;3,4-Dichloro-5-sulfamylbenzenesulfonamide;4,5-Dichloro-1,3-disulfamoylbenzene;4,5-Dichloro-m-benzenedisulfonamide;Antidrasi;Daramide;Daranide;Dichlorophenamide;Dichlorphenamide;Diclofenamid;
NameDiclofenamide
CAS120-97-8
Synonymsm-Benzenedisulfonamide,4,5-dichloro- (6CI,7CI,8CI);1,3-Disulfamoyl-4,5-dichlorobenzene;1,3-Disulfamyl-4,5-dichlorobenzene;3,4-Dichloro-5-sulfamylbenzenesulfonamide;4,5-Dichloro-1,3-disulfamoylbenzene;4,5-Dichloro-m-benzenedisulfonamide;Antidrasi;Daramide;Daranide;Dichlorophenamide;Dichlorphenamide;Diclofenamid;
EINECS(EC#)204-440-6
Molecular FormulaC6H6Cl2N2O4S2
Molecular Weight305.16
Appearancewhite or nearly white crystalline powder
refractive index1.596
Hazard Xn: Harmful;
Risk R63
Safety
Hazard Codes:
Xn
Risk Statements: 63
R63: Possible risk of harm to the unborn child.
Safety Statements: 36
S36: Wear suitable protective clothing.
RTECS: CZ9200000
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. When heated to decomposition it emits very toxic fumes of Cl−, NOx, and SOx.
Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
dog |
LD50 |
intravenous |
200mg/kg (200mg/kg) |
|
"Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 41, 1969. |
mouse |
LD50 |
intraperitoneal |
304mg/kg (304mg/kg) |
|
Therapie. Vol. 19, Pg. 1423, 1964. |
mouse |
LD50 |
intravenous |
643mg/kg (643mg/kg) |
|
"Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 41, 1969. |
mouse |
LD50 |
oral |
1710mg/kg (1710mg/kg) |
|
"Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 41, 1969. |
rat |
LD50 |
intraperitoneal |
1244mg/kg (1244mg/kg) |
|
Drugs in Japan Vol. -, Pg. 446, 1990. |
rat |
LD50 |
oral |
10070mg/kg (10070mg/kg) |
|
Drugs in Japan Vol. -, Pg. 446, 1990. |