Pregna-1,4-diene-3,11,20-trione,17,21-dihydroxy-16-methyl-, (16b)- cas no:1247-42-3
Synonyms: Pregna-1,4-diene-3,11,20-trione,17,21-dihydroxy-16b-methyl- (6CI,7CI,8CI);16b-Methylprednisone;17,21-Dihydroxy-16b-methylpregna-1,4-diene-3,11,20-trione;Beta;Betalone;Betanisona;Betapar;Betapred;Bitanisone;Deltacortene Beta;Deltisona B;Lepicortin-Beta;Sch4358;Prednisone Base;
NamePregna-1,4-diene-3,11,20-trione,17,21-dihydroxy-16-methyl-, (16b)-
CAS1247-42-3
SynonymsPregna-1,4-diene-3,11,20-trione,17,21-dihydroxy-16b-methyl- (6CI,7CI,8CI);16b-Methylprednisone;17,21-Dihydroxy-16b-methylpregna-1,4-diene-3,11,20-trione;Beta;Betalone;Betanisona;Betapar;Betapred;Bitanisone;Deltacortene Beta;Deltisona B;Lepicortin-Beta;Sch4358;Prednisone Base;
EINECS(EC#)214-996-1
Molecular FormulaC22H28O5
Molecular Weight372.45472
Appearancewhite solid
refractive index1.595
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU4154090
- CHEMICAL NAME :
- Pregna-1,4-diene-3,11,20-trione,
17,21-dihydroxy-16-beta-methyl-
- CAS REGISTRY NUMBER :
- 1247-42-3
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C22-H28-O5
- MOLECULAR WEIGHT :
- 372.50
- WISWESSER LINE NOTATION :
- L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ G1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 14 mg/kg
- SEX/DURATION :
- female 16-22 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - blood and lymphatic
systems (including spleen and marrow)
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
gain)
- REFERENCE :
- EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
Switzerland) V.1- 1945- Volume(issue)/page/year: 30,1098,1974
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 6250 ug/kg
- SEX/DURATION :
- female 15-19 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Effects on Newborn - biochemical and metabolic
- REFERENCE :
- PEREBL Pediatric Research. (Williams & Wilkins Co., 428 E. Preston St.,
Baltimore, MD 21202) V.1- 1967- Volume(issue)/page/year: 11,1042,1977
