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aminoglutethimide cas no:125-84-8

Synonyms: DL-Aminoglutethimide 99 %; 2-(4-aminophenyl)-2-ethylglutarimide; DL-Aminoglutethimide

Identification
Nameaminoglutethimide
CAS125-84-8
SynonymsDL-Aminoglutethimide 99 %; 2-(4-aminophenyl)-2-ethylglutarimide; DL-Aminoglutethimide
EINECS(EC#)204-756-4
Molecular FormulaC13H16N2O2
Molecular Weight232.28
Chemical Properties
Appearancealmost white powder
refractive index1.566
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xi:Irritant;
Risk R36/37/38
Safety

Moderately toxic by intraperitoneal route. Human systemic effects by ingestion: agranulocytosis, dyspnea. Human teratogenic effects by ingestion: urogenital developmental abnormalities. When heated to decomposition it emits toxic fumes of NOx.Safety information of Aminoglutethimide (CAS NO.125-84-8):
Hazard Codes  IrritantXi
Risk Statements 
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements 
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36 Wear suitable protective clothing
RIDADR  3249
WGK Germany  3
RTECS  MA4026950
HazardClass  6.1(b)
PackingGroup  III


Toxicity
1.    

orl-wmn TDLo:20,500 mg/kg/94W-I:BLD

    BMJOAE    British Medical Journal. 291 (1985),970.
2.    

orl-man LDLo:21 mg/kg/3D-I:PUL

    AIMEAS    Annals of Internal Medicine. 105 (1986),633.
3.    

ipr-mus LD50:625 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 18 (1975),736.

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