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5-Pyrimidinemethanol, a-cyclopropyl-a-(4-methoxyphenyl)- cas no:12771-68-5

Synonyms: 5-Pyrimidinemethanol,a-cyclopropyl-a-(p-methoxyphenyl)- (8CI);A-Rest;EL 531;Reducymol;Thritone;a-Cyclopropyl-a-(4-methoxyphenyl)-5-pyrimidinemethanol;a-Cyclopropyl-a-(4-methoxyphenyl)-5-pyrimidinylmethanol;a-Cyclopropyl-a-(methoxyphenyl)-5-pyrimidinemethanol;

Identification
Name5-Pyrimidinemethanol, a-cyclopropyl-a-(4-methoxyphenyl)-
CAS12771-68-5
Synonyms5-Pyrimidinemethanol,a-cyclopropyl-a-(p-methoxyphenyl)- (8CI);A-Rest;EL 531;Reducymol;Thritone;a-Cyclopropyl-a-(4-methoxyphenyl)-5-pyrimidinemethanol;a-Cyclopropyl-a-(4-methoxyphenyl)-5-pyrimidinylmethanol;a-Cyclopropyl-a-(methoxyphenyl)-5-pyrimidinemethanol;
EINECS(EC#)235-814-7
Molecular FormulaC15H16N2O2
Molecular Weight256.3
Chemical Properties
AppearanceWhite to yellow powder
refractive index1.618
storage temp2-8°C
Safety Data

Safety

Safety information of Ancymidol (CAS NO.12771-68-5):
Safety Statements 
22 Do not breathe dust
24/25 Avoid contact with skin and eyes
WGK Germany  3
RTECS  UV9280000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 oral > 500mg/kg (500mg/kg)   Pesticide Manual. Vol. 9, Pg. 34, 1991.
dog LD50 oral > 500mg/kg (500mg/kg)   Pesticide Manual. Vol. 9, Pg. 34, 1991.
monkey LD50 oral > 500mg/kg (500mg/kg)   Pesticide Manual. Vol. 9, Pg. 34, 1991.
mouse LD50 intraperitoneal 500mg/kg (500mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 17, Pg. S151, 1992.
mouse LD50 oral 5gm/kg (5000mg/kg)   Pesticide Manual. Vol. 9, Pg. 34, 1991.
mouse LD50 subcutaneous > 10gm/kg (10000mg/kg)   Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 17, Pg. S151, 1992.
rabbit LD50 skin > 200mg/kg (200mg/kg)   Farm Chemicals Handbook. Vol. -, Pg. C26, 1991.
rat LCLo inhalation > 5600mg/m3/4H (5600mg/m3)   Pesticide Manual. Vol. 9, Pg. 34, 1991.
rat LD50 intraperitoneal 780mg/kg (780mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 17, Pg. S151, 1992.
rat LD50 oral 4500mg/kg (4500mg/kg)   Farm Chemicals Handbook. Vol. -, Pg. C26, 1991.
rat LD50 subcutaneous > 10gm/kg (10000mg/kg)   Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 17, Pg. S151, 1992.

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KRKA D.D NOVO MESTO
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