129-74-8|Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-,hydrochloride (1:2)Products Supply

Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-,hydrochloride (1:2) cas no:129-74-8

Synonyms: Piperazine,1-(p-tert-butylbenzyl)-4-(p-chloro-a-phenylbenzyl)-, dihydrochloride (6CI,7CI,8CI);Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-,dihydrochloride (9CI);1-(p-tert-Butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazine dihydrochloride;1-p-Chlorobenzhydryl-4-p-(t)-butylbenzylpiperazine dihydrochloride;Bucladin S;Buclina;Buclizine dihydrochloride;Buclodin;Histabutyzine hydrochloride;Longifene;NSC 25141;Vibazine;Vibazine Hydrochloride;

Identification

NamePiperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-,hydrochloride (1:2)
CAS129-74-8
SynonymsPiperazine,1-(p-tert-butylbenzyl)-4-(p-chloro-a-phenylbenzyl)-, dihydrochloride (6CI,7CI,8CI);Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-,dihydrochloride (9CI);1-(p-tert-Butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazine dihydrochloride;1-p-Chlorobenzhydryl-4-p-(t)-butylbenzylpiperazine dihydrochloride;Bucladin S;Buclina;Buclizine dihydrochloride;Buclodin;Histabutyzine hydrochloride;Longifene;NSC 25141;Vibazine;Vibazine Hydrochloride;
EINECS(EC#)204-962-4
Molecular FormulaC₂₈H₃₅Cl₃N₂
Molecular Weight433.03

Chemical Properties

AppearanceOff-White Powder

Safety Data

Safety

Poison by intraperitoneal route. An experimental teratogen. When heated to decomposition it emits very toxic fumes of NO_x and HCl.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	430mg/kg (430mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 43, Pg. 653, 1954.
mouse	LD50	oral	2100mg/kg (2100mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 43, Pg. 653, 1954.

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Espee Biopharma & Finechem LLC: Tel:+1-(201)-253-9053, 248-990-7454; Address: 2761 Manu ct, Glenview, Illinois 60026,

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Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-,hydrochloride (1:2) cas no:129-74-8

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