Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-,hydrochloride (1:2) cas no:129-74-8
Synonyms: Piperazine,1-(p-tert-butylbenzyl)-4-(p-chloro-a-phenylbenzyl)-, dihydrochloride (6CI,7CI,8CI);Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-,dihydrochloride (9CI);1-(p-tert-Butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazine dihydrochloride;1-p-Chlorobenzhydryl-4-p-(t)-butylbenzylpiperazine dihydrochloride;Bucladin S;Buclina;Buclizine dihydrochloride;Buclodin;Histabutyzine hydrochloride;Longifene;NSC 25141;Vibazine;Vibazine Hydrochloride;
NamePiperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-,hydrochloride (1:2)
CAS129-74-8
SynonymsPiperazine,1-(p-tert-butylbenzyl)-4-(p-chloro-a-phenylbenzyl)-, dihydrochloride (6CI,7CI,8CI);Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-,dihydrochloride (9CI);1-(p-tert-Butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazine dihydrochloride;1-p-Chlorobenzhydryl-4-p-(t)-butylbenzylpiperazine dihydrochloride;Bucladin S;Buclina;Buclizine dihydrochloride;Buclodin;Histabutyzine hydrochloride;Longifene;NSC 25141;Vibazine;Vibazine Hydrochloride;
EINECS(EC#)204-962-4
Molecular FormulaC28H35Cl3N2
Molecular Weight433.03
AppearanceOff-White Powder
Safety
Poison by intraperitoneal route. An experimental teratogen. When heated to decomposition it emits very toxic fumes of NOx and HCl.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
430mg/kg (430mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: EXCITEMENT
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 43, Pg. 653, 1954. |
| mouse |
LD50 |
oral |
2100mg/kg (2100mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: EXCITEMENT
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 43, Pg. 653, 1954. |
