13009-99-9|Mafenide acetateProducts Supply - Chemical intermediates Network

Mafenide acetate cas no:13009-99-9

Synonyms: Winthrocine;Mafenide acetate (JAN/USP);p-Toluenesulfonamide, alpha-amino-, monoacetate;Sulfamylon (TN);alpha-Aminotoluene-4-sulphonamide monoacetate;α-aminotoluene-4-sulphonamide monoacetate;Mafenide acetate (USP31);Mafenide acetate [USAN:JAN];alpha-Amino-p-toluenesulfonamide monoacetate;Maphenide acetate;Benzenesulfonamide, 4-(aminomethyl)-, monoacetate;p-Aminomethylbenzenesulfonamide acetate;4-(Aminomethyl)benzenesulfonamide monoacetate;acetic acid; 4-(aminomethyl)benzenesulfonamide;Sulfamilon;

Identification

NameMafenide acetate
CAS13009-99-9
SynonymsWinthrocine;Mafenide acetate (JAN/USP);p-Toluenesulfonamide, alpha-amino-, monoacetate;Sulfamylon (TN);alpha-Aminotoluene-4-sulphonamide monoacetate;α-aminotoluene-4-sulphonamide monoacetate;Mafenide acetate (USP31);Mafenide acetate [USAN:JAN];alpha-Amino-p-toluenesulfonamide monoacetate;Maphenide acetate;Benzenesulfonamide, 4-(aminomethyl)-, monoacetate;p-Aminomethylbenzenesulfonamide acetate;4-(Aminomethyl)benzenesulfonamide monoacetate;acetic acid; 4-(aminomethyl)benzenesulfonamide;Sulfamilon;
EINECS(EC#)235-855-0
Molecular FormulaC₇H₁₀N₂O₂S^.C₂H₄O₂
Molecular Weight246.28346

Chemical Properties

AppearanceCrystalline Solid

Safety Data

Safety

Moderately toxic by intravenous and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Used as an antibacterial agent. When heated to decomposition it emits very toxic fumes of NO_x and SO_x.
Safety information of Mafenide acetate (CAS NO.13009-99-9):
WGK Germany: 3

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	5425mg/kg (5425mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(8), Pg. 50, 1987.
mammal (species unspecified)	LC	inhalation	> 320mg/m³ (320mg/m³)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(8), Pg. 50, 1987.
mouse	LD50	intraperitoneal	2322mg/kg (2322mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(8), Pg. 50, 1987.
mouse	LD50	intravenous	1580mg/kg (1580mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Life Sciences. Vol. 5, Pg. 2279, 1966.
mouse	LD50	oral	10183mg/kg (10183mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(8), Pg. 50, 1987.
mouse	LD50	subcutaneous	> 5gm/kg (5000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS	Yakkyoku. Pharmacy. Vol. 30, Pg. 1517, 1979.
rat	LD50	intraperitoneal	1560mg/kg (1560mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 884, 1979.
rat	LD50	intravenous	1730mg/kg (1730mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 884, 1979.
rat	LD50	oral	9212mg/kg (9212mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(8), Pg. 50, 1987.
rat	LD50	subcutaneous	> 5gm/kg (5000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS	Yakkyoku. Pharmacy. Vol. 30, Pg. 1517, 1979.

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Credimate Trading Limited: Tel:+86-(21)-57429129; Address: Suite 302, No. 503 Guhuaxincun Area B, Nanqiao, Fengxian, Shanghai 201400,

Unite (Suzhou ) Pharmtech Co., Ltd.: Tel:86-512-87666020; Address: B Building, No.31 North Dongwu Rd.,

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HBCChem, Inc.: Tel:+1-510-219-6317; Address:

suchem pharma co.,limited: Tel:86-57781172668; Address: wenzhou, China

Shanghai Hope Chem Co., Ltd.: Tel:86-21-61723543; Address: Room508, Building1, No.88 CaiLun Road Zhangjiang H

Jinlan Pharm-Drugs Technology Co., Limited: Tel:86-571-85829152; Address: Room 606, Fuyi Center, #298 Quanfuqiao Road, Jiang

Finetech Industry limited.: Tel:86-27-87465837; Address: chukang Road, Wuhan, Hubei 430073,

Hangzhou J&H Chemical Co., Ltd: Tel:86-571-87396430; Address: No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

Wuhan Dahua Weiye Pharmaceutical Co.,Ltd: Tel:86-27-59335372; Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

Hangzhou J&H Chemical Co., Ltd: Tel:86-571-87396430; Address: No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

Wuhan Dahua Weiye Pharmaceutical Co.,Ltd: Tel:86-27-59335372; Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China

Wuhan Dahua Weiye Pharmaceutical Co.,Ltd: Tel:86-27-59335372; Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China

Wuhan Senwayer Century chemical Co.,Ltd: Tel:86-27-59009407; Address: 20#Xudong Street,Wuhan China

Mafenide acetate cas no:13009-99-9

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