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2-Pyridinepropanamine, g-(4-chlorophenyl)-N,N-dimethyl- cas no:132-22-9

Synonyms: Pyridine,2-[p-chloro-a-[2-(dimethylamino)ethyl]benzyl]-(8CI); (?à)-Chloropheniramine; (?à)-Chlorpheniramine;1-(p-Chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane; 2-[p-Chloro-a-[2-(dimethylamino)ethyl]benzyl]pyridine;3-(p-Chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine; 4-Chloropheniramine;Allergican; Chloropheniramine; Chlorophenylpyridamine; Chloroprophenpyridamine;Chlorphenamine; Chlorpheniramine; Chlorprophenpyridamine; Haynon;RS-Chlorpheniramine;dl-1-(p-Chlorophenyl)-1-(2-pyridyl)-3-(dimethylamino)propane; g-(4-Chlorophenyl)-g-(2-pyridyl)propyldimethylamine

Identification
Name2-Pyridinepropanamine, g-(4-chlorophenyl)-N,N-dimethyl-
CAS132-22-9
SynonymsPyridine,2-[p-chloro-a-[2-(dimethylamino)ethyl]benzyl]-(8CI); (?à)-Chloropheniramine; (?à)-Chlorpheniramine;1-(p-Chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane; 2-[p-Chloro-a-[2-(dimethylamino)ethyl]benzyl]pyridine;3-(p-Chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine; 4-Chloropheniramine;Allergican; Chloropheniramine; Chlorophenylpyridamine; Chloroprophenpyridamine;Chlorphenamine; Chlorpheniramine; Chlorprophenpyridamine; Haynon;RS-Chlorpheniramine;dl-1-(p-Chlorophenyl)-1-(2-pyridyl)-3-(dimethylamino)propane; g-(4-Chlorophenyl)-g-(2-pyridyl)propyldimethylamine
EINECS(EC#)205-054-0
Molecular FormulaC16H19 Cl N2
Molecular Weight274.82
Chemical Properties
refractive index1.565
Safety Data

Safety

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic vapors of NOx and Cl.


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 125mg/kg (125mg/kg)   Yakugaku Zasshi. Journal of Pharmacy. Vol. 92, Pg. 1339, 1972.
mouse LD50 intravenous 20mg/kg (20mg/kg)   Medizinische Welt. Vol. 17, Pg. 2791, 1966.
mouse LD50 oral 121mg/kg (121mg/kg)   Medizinische Welt. Vol. 17, Pg. 2791, 1966.
mouse LD50 subcutaneous 160mg/kg (160mg/kg)   Bollettino Chimico Farmaceutico. Vol. 111, Pg. 293, 1972.
rabbit LD50 intravenous 22mg/kg (22mg/kg)   Medizinische Welt. Vol. 17, Pg. 2791, 1966.
rat LD50 oral 118mg/kg (118mg/kg)   Medizinische Welt. Vol. 17, Pg. 2791, 1966.

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