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2-Propanol,1-[(1-methylethyl)amino]-3-[2-(2-propen-1-yl)phenoxy]-, hydrochloride (1:1) cas no:13707-88-5

Synonyms: 2-Propanol,1-(o-allylphenoxy)-3-(isopropylamino)-, hydrochloride (8CI); 2-Propanol,1-[(1-methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-, hydrochloride (9CI); (?à)-1-(o-Allylphenoxy)-3-isopropylamino-2-propanolhydrochloride; (?à)-Alprenololhydrochloride; 1-(2-Allylphenoxy)-2-hydroxy-3-isopropylaminopropanehydrochloride; 1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol hydrochloride;Alfeprol; Alprenolol hydrochloride; Apllobal; Applobal; Aprobal; Aptin; Aptine;Aptol Duriles; Betaptin; DL-1-(o-Allylphenoxy)-3-isopropylamino-2-propanolhydrochloride; Dimacor; Gubernal; H 56/28; Regletin; Yobir; dl-Alprenololchloride

Identification
Name2-Propanol,1-[(1-methylethyl)amino]-3-[2-(2-propen-1-yl)phenoxy]-, hydrochloride (1:1)
CAS13707-88-5
Synonyms2-Propanol,1-(o-allylphenoxy)-3-(isopropylamino)-, hydrochloride (8CI); 2-Propanol,1-[(1-methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-, hydrochloride (9CI); (?à)-1-(o-Allylphenoxy)-3-isopropylamino-2-propanolhydrochloride; (?à)-Alprenololhydrochloride; 1-(2-Allylphenoxy)-2-hydroxy-3-isopropylaminopropanehydrochloride; 1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol hydrochloride;Alfeprol; Alprenolol hydrochloride; Apllobal; Applobal; Aprobal; Aptin; Aptine;Aptol Duriles; Betaptin; DL-1-(o-Allylphenoxy)-3-isopropylamino-2-propanolhydrochloride; Dimacor; Gubernal; H 56/28; Regletin; Yobir; dl-Alprenololchloride
EINECS(EC#)237-244-4
Molecular FormulaC15H23 N O2 . Cl H
Molecular Weight285.80956
Chemical Properties
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Poison by ingestion, subcutaneous, intravenous and intraperitoneal routes. Human systemic effects by ingestion: change in heart rate. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also ALLYL COMPOUNDS.
Hazard Codes HarmfulXn
Risk Statements 22
R22:Harmful if swallowed.
RIDADR 3249
WGK Germany 3
RTECS UA5425000
HazardClass 6.1(b)
PackingGroup III


Toxicity
1.    

orl-man TDLo:571 µg/kg:CVS

    KIZSB8    Kyorin Igakukai Zasshi. Journal of the Kyorin Medical Society. 6 (4)(1975),209.
2.    

orl-rat LD50:590 mg/kg

    KSRNAM    Kiso to Rinsho. Clinical Report. 11 (1977),1321.
3.    

scu-rat LD50:290 mg/kg

    KSRNAM    Kiso to Rinsho. Clinical Report. 11 (1977),1321.
4.    

scu-mus LD50:215 mg/kg

    KSRNAM    Kiso to Rinsho. Clinical Report. 11 (1977),1321.
5.    

orl-mus LD50:184 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 202 (1973),79.
6.    

orl-dog LD50:383 mg/kg

    GNRIDX    Gendai no Rinsho. 3 (1969),614.
7.    

scu-dog LD50:92 mg/kg

    GNRIDX    Gendai no Rinsho. 3 (1969),614.
8.    

ivn-dog LD50:18 mg/kg

    GNRIDX    Gendai no Rinsho. 3 (1969),614.

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