145-41-5|Sodium dehydrocholateProducts Supply - Chemical intermediates Network

Sodium dehydrocholate cas no:145-41-5

Synonyms: 5b-Cholan-24-oic acid,3,7,12-trioxo-, sodium salt (8CI);Dehydrocholic acid sodium salt (6CI);Biliron;Biliton;Carachol;Decholin sodium;Decholin sodium salt;Dehydrocholatesodium;Dilabil sodium;Dycholium;Sodium 3,7,12-triketocholanate;Sodium3,7,12-trioxo-5b-cholanate;

Identification

NameSodium dehydrocholate
CAS145-41-5
Synonyms5b-Cholan-24-oic acid,3,7,12-trioxo-, sodium salt (8CI);Dehydrocholic acid sodium salt (6CI);Biliron;Biliton;Carachol;Decholin sodium;Decholin sodium salt;Dehydrocholatesodium;Dilabil sodium;Dycholium;Sodium 3,7,12-triketocholanate;Sodium3,7,12-trioxo-5b-cholanate;
EINECS(EC#)205-652-1
Molecular FormulaC₂₄H₃₄O₅.Na
Molecular Weight402.52376

Chemical Properties

AppearanceCOA
refractive index27 ° (C=5, H2O)

Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Hazard Codes: Harmful Xn
Risk Statements: 22-37
R22: Harmful if swallowed.
R37: Irritating to respiratory system
Safety Statements: 22-36
S22: Do not breathe dust.
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: FZ2500000
F: 3-9

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	1480mg/kg (1480mg/kg)		Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 280, 1970.
mouse	LD50	intravenous	1100mg/kg (1100mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Yonago Igaku Zasshi. Journal of the Yonago Medical Association. Vol. 25, Pg. 70, 1974.
mouse	LD50	oral	2150mg/kg (2150mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Yonago Igaku Zasshi. Journal of the Yonago Medical Association. Vol. 25, Pg. 70, 1974.
mouse	LD50	subcutaneous	1350mg/kg (1350mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Yonago Igaku Zasshi. Journal of the Yonago Medical Association. Vol. 25, Pg. 70, 1974.
rabbit	LDLo	intravenous	1gm/kg (1000mg/kg)	CARDIAC: OTHER CHANGES BLOOD: OTHER CHANGES GASTROINTESTINAL: OTHER CHANGES	Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 52, Pg. 779, 1926.
rat	LD50	intraperitoneal	1100mg/kg (1100mg/kg)		Chimica Therapeutica. Vol. 5, Pg. 188, 1970.
rat	LD50	intravenous	887mg/kg (887mg/kg)		Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 280, 1970.
rat	LD50	oral	3755mg/kg (3755mg/kg)		German Offenlegungsschrift Patent Document. Vol. 2630169,
rat	LD50	subcutaneous	2300mg/kg (2300mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Yonago Igaku Zasshi. Journal of the Yonago Medical Association. Vol. 25, Pg. 70, 1974.

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Sodium dehydrocholate cas no:145-41-5

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