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Home > products > Pregna-1,4-diene-3,20-dione,21-(2,2-dimethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-methyl-, (6a,11b,16a)-

Pregna-1,4-diene-3,20-dione,21-(2,2-dimethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-methyl-, (6a,11b,16a)- cas no:2002-29-1

Synonyms: Pregna-1,4-diene-3,20-dione,6a,9-difluoro-11b,17,21-trihydroxy-16a-methyl-, 21-pivalate (7CI,8CI);Pivalic acid, 21-ester with 6a,9-difluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione (8CI);6a,9a-Difluoro-11b,17a,21-trihydroxy-16a-methyl-1,4-pregnadiene-3,20-dione21-pivalate;6a,9a-Difluoro-16a-methylprednisolone 21-pivalate;Flumetasone 21-pivalate;Flumetasone pivalate;Flumethasone pivalate;Locacorten;Locorten;Lorinden;Losalen;NSC 107680;Flumethsone? Pivalate;

Identification
NamePregna-1,4-diene-3,20-dione,21-(2,2-dimethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-methyl-, (6a,11b,16a)-
CAS2002-29-1
SynonymsPregna-1,4-diene-3,20-dione,6a,9-difluoro-11b,17,21-trihydroxy-16a-methyl-, 21-pivalate (7CI,8CI);Pivalic acid, 21-ester with 6a,9-difluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione (8CI);6a,9a-Difluoro-11b,17a,21-trihydroxy-16a-methyl-1,4-pregnadiene-3,20-dione21-pivalate;6a,9a-Difluoro-16a-methylprednisolone 21-pivalate;Flumetasone 21-pivalate;Flumetasone pivalate;Flumethasone pivalate;Locacorten;Locorten;Lorinden;Losalen;NSC 107680;Flumethsone? Pivalate;
EINECS(EC#)217-901-1
Molecular FormulaC27H36F2O6
Molecular Weight494.58
Chemical Properties
refractive index1.55
Safety Data

Hazard Xn:Harmful;
Risk R40
Safety

Hazard Codes of Flumetasone pivalate (CAS NO.2002-29-1): HarmfulXn
Risk Statements: 40 
R40: Limited evidence of a carcinogenic effect.
Safety Statements: 22-36 
S22: Do not breathe dust. 
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: TU3832010


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 705, 1982.
rat LD50 oral > 2gm/kg (2000mg/kg)   Drugs in Japan Vol. 6, Pg. 705, 1982.

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Tianjin Harmony Technology Development Co., Ltd.
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Arrow Chemical Inc
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Vinchem, Inc.
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Tianjin Topwork Fine Chemical Co., Ltd.
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Guangzhou Topwork Chemical Co., Ltd.
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Shanghai Fulland Chemicals Ltd.
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Tianjin Hi-Tesion Bio&Chem Co., Ltd.
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TaiZhou HiKong Chemical Co., Ltd.
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Address: Taizhou Economic Technical Development Zone, Taizhou, Zhejiang 318000,
KINFON PHARMACEUTICAL AND CHEMICAL CO.LTD
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Address: 32F,Duhe Plaza, Lijiatuo Street, Banan Dist,Chongq
HangZhou Peak Chemical Co.,Ltd
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Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China
Rota Pharm & Chem Co., Ltd.
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Address: Room 401,Hangzhou Friendship Plaza,No.74 Bbaochu Road, Hangzhou, Zhejiang,
Shanghai Matt Chemicals Co., Ltd
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Address: Huqingping road 1768 (shengbao startup hub), Qingpu District, Shanghai City
TIANJIN HI-TESION BIO & CHEM CO., LTD.
Tel:+86-22-23725099
Address: C1506, WANHAO MANSION, NO. 333 BINCHUIXI ROAD, NANAKAI DISTRICT, TIANJIN, CHINA
TIANJIN HI-TESION BIO&CHEM CO., LTD
Tel:0086-22-23725099
Address: No.333 Binshuixi Road

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