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L-Leucine,N-[(phenylmethoxy)carbonyl]- cas no:2018-66-8

Synonyms: Leucine,N-carboxy-, N-benzyl ester (6CI);(Benzyloxycarbonyl)leucine;(Carbobenzyloxy)-L-leucine;CBZ-L-leucine;L-(Carbobenzyloxy)leucine;L-N-(Benzyloxycarbonyl)leucine;N-(Benzyloxycarbonyl)leucine;N-(Carbobenzoxy)leucine;N-Carbobenzyloxy-L-leucine;N-Carboxy-L-leucine N-benzyl ester;NSC60039;Z-Leu-OH;

Identification
NameL-Leucine,N-[(phenylmethoxy)carbonyl]-
CAS2018-66-8
SynonymsLeucine,N-carboxy-, N-benzyl ester (6CI);(Benzyloxycarbonyl)leucine;(Carbobenzyloxy)-L-leucine;CBZ-L-leucine;L-(Carbobenzyloxy)leucine;L-N-(Benzyloxycarbonyl)leucine;N-(Benzyloxycarbonyl)leucine;N-(Carbobenzoxy)leucine;N-Carbobenzyloxy-L-leucine;N-Carboxy-L-leucine N-benzyl ester;NSC60039;Z-Leu-OH;
EINECS(EC#)217-960-3
Molecular FormulaC14H19NO4
Molecular Weight265.31
Chemical Properties
Appearanceviscous liquid
alpha-17 o (C=2, ETHANOL)
refractive index1.512
storage temp2-8°C
Safety Data

Hazard Xn:Harmful
Risk R10;R20/22;R37/38;R40;R41
Safety

Hazard Codes of?N-Cbz-L-Leucine (CAS NO.2018-66-8):?HarmfulXn
Risk Statements: 10-40-41-36/37/38-20/21/22?
R10: Flammable.?
R40: Limited evidence of a carcinogenic effect.?
R41: Risk of serious damage to the eyes.?
R36/37/38: Irritating to eyes, respiratory system and skin.?
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 16-26-36/37/39-45?
S16: Keep away from sources of ignition.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
RTECS: OH2921000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravaginal > 1gm/kg (1000mg/kg) ? Journal of Pharmaceutical Sciences. Vol. 68, Pg. 696, 1979.

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