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Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy- cas no:2086-83-1

Synonyms: Berbinium,7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)- (8CI);Umbellatine(6CI);5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium;Berbericine;Berberin;Majarine;Thalsine;Umbellatin;

Identification
NameBenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-
CAS2086-83-1
SynonymsBerbinium,7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)- (8CI);Umbellatine(6CI);5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium;Berbericine;Berberin;Majarine;Thalsine;Umbellatin;
EINECS(EC#)218-229-1
Molecular FormulaC20H18NO4
Molecular Weight336.36
Chemical Properties
AppearanceYellow
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Safety

An alkaloid poison by ingestion and subcutaneous routes. In humans, toxic doses lower the body temperature, increase peristalsis, and cause death by central paralysis. Mutation data reported. Should carry a poison label. Should never be ingested without the advice of a physician. Should not be handled excessively since it may be absorbed through the skin and have a toxic effect upon the body. An antimalarial agent. When heated to decomposition it emits highly toxic fumes of NOx.


Toxicity
1.    

mmo-sat 100 µmol/L

    AMACCQ    Antimicrobial Agents and Chemotherapy. 9 (1976),77.
2.    

dnd-esc 10 µmol/L

    MUREAV    Mutation Research. 89 (1981),95.
3.    

orl-mus LD50:329 mg/kg

    YKKZAJ    Yakugaku Zasshi. Journal of Pharmacy. 82 (1962),726.
4.    

scu-mus LD50:18 mg/kg

    RPTOAN    Russian Pharmacology and Toxicology. 31 (1968),129.
5.    

scu-rbt LDLo:100 mg/kg

    HBAMAK    Abdernaldens Handbuch der Biologischen Arbeitsmethoden. 4 (1935),1289.

supplier list

N-Techem International Co.Ltd.
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Enze Chemicals Co.,Ltd
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APAC Pharmaceutical, LLC
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Kouting Chemical Co.,Ltd
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Anhui Ruisen Biological Technology Co., Ltd.
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TPNChina
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Wuhan Dahua Weiye Pharmaceutical Co.,Ltd
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Nanjing Bangnuo Biotechnology Co., Ltd
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Nanjing Bangnuo Biotechnology Co., Ltd
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SZ . Phystandard Bio-Tech Co., Ltd. (Overseas Business Division)
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Boc Sciences
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Jinan Haohua Industry Co., Ltd.
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Xian App-Chem Bio (Tech) Co., Ltd.
Tel:+86-29-88327527 ext.805
Address: C601,Gazelle Valley,No.69 Jinye RD.,Xi'an,710077,China
Shanghai Standard Biotech Co., Ltd.
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Address: Room 206, 1011 Halei Road, Shanghai 201203,
Shanghai Forever Biotech Co., Ltd.
Tel:+86-(21)-6973-4790
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