Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy- cas no:2086-83-1
Synonyms: Berbinium,7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)- (8CI);Umbellatine(6CI);5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium;Berbericine;Berberin;Majarine;Thalsine;Umbellatin;
NameBenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-
CAS2086-83-1
SynonymsBerbinium,7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)- (8CI);Umbellatine(6CI);5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium;Berbericine;Berberin;Majarine;Thalsine;Umbellatin;
EINECS(EC#)218-229-1
Molecular FormulaC20H18NO4
Molecular Weight336.36
AppearanceYellow
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety
An alkaloid poison by ingestion and subcutaneous routes. In humans, toxic doses lower the body temperature, increase peristalsis, and cause death by central paralysis. Mutation data reported. Should carry a poison label. Should never be ingested without the advice of a physician. Should not be handled excessively since it may be absorbed through the skin and have a toxic effect upon the body. An antimalarial agent. When heated to decomposition it emits highly toxic fumes of NOx.
| 1. |
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mmo-sat 100 µmol/L
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AMACCQ Antimicrobial Agents and Chemotherapy. 9 (1976),77. |
| 2. |
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dnd-esc 10 µmol/L
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MUREAV Mutation Research. 89 (1981),95. |
| 3. |
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orl-mus LD50:329 mg/kg
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YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. 82 (1962),726. |
| 4. |
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scu-mus LD50:18 mg/kg
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RPTOAN Russian Pharmacology and Toxicology. 31 (1968),129. |
| 5. |
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scu-rbt LDLo:100 mg/kg
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HBAMAK Abdernaldens Handbuch der Biologischen Arbeitsmethoden. 4 (1935),1289. |
