betamethasone 17-valerate cas no:2152-44-5
Synonyms: betamethasone pentanoate; Betamethasone Valerate; 1,4-Pregnadiene-11b,17a,21-triol-9a-fluoro-16b-methyl-3,20-dione 17-valerate; 9-Fluoro-11beta,17,21-trihydroxy-16bet; methylpregna-1,4-diene-3,20-dione 17-valerate; VALISONE
(11-beta,16-beta)-l)oxy); 17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione-9-fluoro-11-bet; 17-valerate; Betamethasonevalerateester; betnovateat; celestoderm
Namebetamethasone 17-valerate
CAS2152-44-5
Synonymsbetamethasone pentanoate; Betamethasone Valerate; 1,4-Pregnadiene-11b,17a,21-triol-9a-fluoro-16b-methyl-3,20-dione 17-valerate; 9-Fluoro-11beta,17,21-trihydroxy-16bet; methylpregna-1,4-diene-3,20-dione 17-valerate; VALISONE
(11-beta,16-beta)-l)oxy); 17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione-9-fluoro-11-bet; 17-valerate; Betamethasonevalerateester; betnovateat; celestoderm
EINECS(EC#)218-439-3
Molecular FormulaC27H37FO6
Molecular Weight476.577483
AppearanceMixed with a solvent.
refractive index1.56
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass4.3
Hazard Xn:Harmful
Risk R48
Safety
Poison by subcutaneous route. Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of F?.
Hazard Codes:?
Xn
Risk Statements: 48?
R48:Danger of serious damage to health by prolonged exposure.
Safety Statements: 22-24/25?
S24/25:Avoid contact with skin and eyes.?
S22:Do not breathe dust.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 2
RTECS: TU3835000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
632mg/kg (632mg/kg) |
? |
Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973. |
| mouse |
LD50 |
oral |
4067mg/kg (4067mg/kg) |
? |
Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973. |
| mouse |
LD50 |
subcutaneous |
496mg/kg (496mg/kg) |
? |
Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973. |
| rabbit |
LD50 |
subcutaneous |
61200ug/kg (61.2mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" |
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984. |
| rat |
LD50 |
intraperitoneal |
> 4500mg/kg (4500mg/kg) |
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984. |
| rat |
LD50 |
oral |
> 3gm/kg (3000mg/kg) |
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984. |
| rat |
LDLo |
subcutaneous |
2gm/kg (2000mg/kg) |
? |
Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 2102, 1977. |
