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4-Aminopyrazolo[3,4-d]pyrimidine cas no:2380-63-4

Synonyms: 4-amino-pyrazolo(3,4-D)pyrimidine

Identification
Name4-Aminopyrazolo[3,4-d]pyrimidine
CAS2380-63-4
Synonyms4-amino-pyrazolo(3,4-D)pyrimidine
EINECS(EC#)219-174-6
Molecular FormulaC5H5N5
Molecular Weight135.13
Chemical Properties
AppearanceBeige powder.
storage tempKeep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard T:Toxic;
Risk R23/24/25;R36/37/38
Safety

Poison by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes ToxicT
Risk Statements 36/37/38-23/24/25
R36/37/38: Pyrazoloadenine (CAS NO. 2380-63-4) is irritating to eyes, respiratory system and skin. 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements 26-36/37/39-45-22 
S22:Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS UR0717000
HazardClass 6.1
PackingGroup III


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 100mg/kg (100mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
Proceedings of the Society for Experimental Biology and Medicine. Vol. 93, Pg. 398, 1956.
mouse LD10 unreported 15mg/kg (15mg/kg) LIVER: OTHER CHANGES Progress in Medical Chemistry. Vol. 7, Pg. 69, 1970.
mouse LD50 intraperitoneal 181mg/kg (181mg/kg)   National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse LD50 oral 180mg/kg (180mg/kg) SENSE ORGANS AND SPECIAL SENSES: CILIARY SPASM: EYE

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: EXCITEMENT
Proceedings of the Society for Experimental Biology and Medicine. Vol. 93, Pg. 398, 1956.
rat LD50 intraperitoneal 228mg/kg (228mg/kg) SENSE ORGANS AND SPECIAL SENSES: CILIARY SPASM: EYE

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: EXCITEMENT
Proceedings of the Society for Experimental Biology and Medicine. Vol. 93, Pg. 398, 1956.
rat LD50 oral 141mg/kg (141mg/kg) SENSE ORGANS AND SPECIAL SENSES: CILIARY SPASM: EYE

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: EXCITEMENT
Proceedings of the Society for Experimental Biology and Medicine. Vol. 93, Pg. 398, 1956.

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