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Mycophenolic acid cas no:24280-93-1

Synonyms: 4-Hexenoic acid,6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)- (8CI);(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoicacid;Melbex;

Identification
NameMycophenolic acid
CAS24280-93-1
Synonyms4-Hexenoic acid,6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)- (8CI);(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoicacid;Melbex;
EINECS(EC#)246-119-3
Molecular FormulaC17H20O6
Molecular Weight320.3371
Chemical Properties
AppearanceWhite to off-white powder
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn:Harmful
Risk R22
Safety

A poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Safety Information of?Mycophenolic acid (CAS NO.24280-93-1):
Hazard Codes:?HarmfulXn
Risk Statements: 22-61-40
R22:Harmful if swallowed.?
R61:May cause harm to the unborn child.?
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 53-45-36/37
S53:Avoid exposure - obtain special instructions before use.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36/37:Wear suitable protective clothing and gloves.
RIDADR: 2811
WGK Germany: 3
RTECS: MP8050000
F: 10
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1. ???

dni-mus:lym 200?nmol/L

??? CNREA8 ?? Cancer Research. 45 (1985),5512.
2. ???

oms-mus:lym 400?nmol/L

??? CNREA8 ?? Cancer Research. 45 (1985),5512.
3. ???

orl-rat LD50:352?mg/kg

??? TOIZAG ?? Toho Igakkai Zasshi. Journal of Medical Society of Toho University. 29 (1982),400.
4. ???

ivn-rat LD50:450?mg/kg

??? PMDCAY ?? Progress in Medical Chemistry. 9 (1973),1.
5. ???

ipr-rat LD50:220?mg/kg

??? TOIZAG ?? Toho Igakkai Zasshi. Journal of Medical Society of Toho University. 29 (1982),400.
6. ???

scu-rat LD50:230?mg/kg

??? TOIZAG ?? Toho Igakkai Zasshi. Journal of Medical Society of Toho University. 29 (1982),400.
7. ???

orl-mus LDLo:1000?mg/kg

??? 85GDA2 ?? CRC Handbook of Antibiotic Compounds, Volumes 1-9. 5 (1981),445.
8. ???

ipr-mus LD50:505?mg/kg

??? TOIZAG ?? Toho Igakkai Zasshi. Journal of Medical Society of Toho University. 29 (1982),400.
9. ???

ivn-mus LDLo:500?mg/kg

??? 85ERAY ?? Antibiotics: Origin, Nature, and Properties. 3 (1978),1740.

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