Penfluridol cas no:26864-56-2
Synonyms: 4-Piperidinol,1-[4,4-bis(p-fluorophenyl)butyl]-4-(4-chloro-a,a,a-trifluoro-m-tolyl)- (8CI);1-[4,4-Bis(p-fluorophenyl)butyl]-4-(4-chloro-a,a,a-trifluoro-m-tolyl)-4-piperidinol;McN-JR 16341; Penfluridol; R 16341; Semap
NamePenfluridol
CAS26864-56-2
Synonyms4-Piperidinol,1-[4,4-bis(p-fluorophenyl)butyl]-4-(4-chloro-a,a,a-trifluoro-m-tolyl)- (8CI);1-[4,4-Bis(p-fluorophenyl)butyl]-4-(4-chloro-a,a,a-trifluoro-m-tolyl)-4-piperidinol;McN-JR 16341; Penfluridol; R 16341; Semap
EINECS(EC#)248-074-5
Molecular FormulaC28H27ClF5NO
Molecular Weight523.97
AppearanceOff-white to white crystalline powder
refractive index1.552
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Hazard T:Toxic;
Risk R25
Safety
Poison by ingestion and intravenous routes. Experimental teratogenic and reproductive effects. A neuroleptic agent. When heated to decomposition it emits very toxic fumes of Cl−, F−, and NOx.
Safety Information of Penfluridol (26864-56-2):
Hazard Codes: T
T: Toxic .gif)
Risk Statements: 25
25: Toxic if swallowed
Safety Statements: 45
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: TN6957000
| 1. |
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orl-rat TDLo:3 mg/kg (lactating female 3D post):REP
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NSAPCC Naunyn-Schmiedeberg’s Archives of Pharmacology. 279 (1973),31. |
| 2. |
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orl-mus TDLo:48 mg/kg (7-12D preg):TER
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OYYAA2 Oyo Yakuri. Pharmacometrics. 13 (1977),581. |
| 3. |
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orl-rat LD50:160 mg/kg
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EJPHAZ European Journal of Pharmacology. 11 (1970),139. |
| 4. |
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orl-mus LD50:87 mg/kg
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EJPHAZ European Journal of Pharmacology. 11 (1970),139. |
| 5. |
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orl-gpg LD50:90 mg/kg
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EJPHAZ European Journal of Pharmacology. 11 (1970),139. |
