Benzenepropanoic acid,4-[[[trans-4-(aminomethyl)cyclohexyl]carbonyl]oxy]-, hydrochloride (1:1) cas no:27724-96-5
Synonyms: Benzenepropanoicacid, 4-[[[4-(aminomethyl)cyclohexyl]carbonyl]oxy]-, hydrochloride, trans-;Benzenepropanoic acid, 4-[[[trans-4-(aminomethyl)cyclohexyl]carbonyl]oxy]-,hydrochloride (9CI); Hydrocinnamic acid, p-hydroxy-,4-(aminomethyl)cyclohexanecarboxylate hydrochloride, trans- (8CI);Cyclohexanecarboxylic acid, 4-(aminomethyl)-, ester with p-hydroxyhydrocinnamicacid, hydrochloride, trans- (8CI); 4-(2-Carboxyethyl)phenyltrans-4-aminomethylcyclohexanecarboxylate hydrochloride; Cetraxatehydrochloride; DV 1006; Neuer; Neuer S
NameBenzenepropanoic acid,4-[[[trans-4-(aminomethyl)cyclohexyl]carbonyl]oxy]-, hydrochloride (1:1)
CAS27724-96-5
SynonymsBenzenepropanoicacid, 4-[[[4-(aminomethyl)cyclohexyl]carbonyl]oxy]-, hydrochloride, trans-;Benzenepropanoic acid, 4-[[[trans-4-(aminomethyl)cyclohexyl]carbonyl]oxy]-,hydrochloride (9CI); Hydrocinnamic acid, p-hydroxy-,4-(aminomethyl)cyclohexanecarboxylate hydrochloride, trans- (8CI);Cyclohexanecarboxylic acid, 4-(aminomethyl)-, ester with p-hydroxyhydrocinnamicacid, hydrochloride, trans- (8CI); 4-(2-Carboxyethyl)phenyltrans-4-aminomethylcyclohexanecarboxylate hydrochloride; Cetraxatehydrochloride; DV 1006; Neuer; Neuer S
Molecular FormulaC17H23 N O4 . Cl H
Molecular Weight341.87
refractive index1.551
Safety
Poison by intravenous route. Moderately toxic by subcutaneous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx and HCl.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
1520mg/kg (1520mg/kg) |
behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea
|
Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 265, 1976. |
| mouse |
LD50 |
intravenous |
666mg/kg (666mg/kg) |
|
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 710, 1979. |
| mouse |
LD50 |
oral |
4310mg/kg (4310mg/kg) |
|
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 21, Pg. 935, 1979. |
| mouse |
LD50 |
subcutaneous |
4210mg/kg (4210mg/kg) |
|
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 710, 1979. |
| rat |
LD50 |
intraperitoneal |
716mg/kg (716mg/kg) |
behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea gastrointestinal: "hypermotility, diarrhea"
|
Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 265, 1976. |
| rat |
LD50 |
intravenous |
298mg/kg (298mg/kg) |
|
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 710, 1979. |
| rat |
LD50 |
oral |
1503mg/kg (1503mg/kg) |
|
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 21, Pg. 935, 1979. |
| rat |
LD50 |
subcutaneous |
1415mg/kg (1415mg/kg) |
|
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 710, 1979. |
