8-Azoniabicyclo[3.2.1]octane,3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8,8-dimethyl-, bromide (1:1), (3-endo)- cas no:2870-71-5

Name8-Azoniabicyclo[3.2.1]octane,3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8,8-dimethyl-, bromide (1:1), (3-endo)-
CAS2870-71-5
Synonyms1aH,5aH-Tropanium, 3a-hydroxy-8-methyl-, bromide, (?à)-tropate (8CI);8-Azoniabicyclo[3.2.1]octane,3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8,8-dimethyl-, bromide, (3-endo)- (9CI);8-Azoniabicyclo[3.2.1]octane,3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8,8-dimethyl-, bromide, endo-(?à)-; 8-Methylatropinium bromide (6CI,7CI);8-Azoniabicyclo[3.2.1]octane,3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8,8-dimethyl-, bromide, endo-; Atropinemethobromide; Atropine methyl bromide; Hyoscyamine methyl bromide;Methylatropine bromide; Methylatropinium bromide; Mintussin; Mydriasin; N-Methylatropinebromide; N-Methylatropinium bromide; NSC 61810; Tropin
EINECS(EC#)220-700-1
Molecular FormulaC18H26 N O3 . Br
Molecular Weight384.36

Hazard Xn,N
Risk 22-50/53
Safety

Hazard Codes of Atropine methobromide (CAS NO.2870-71-5):XnN
Risk Statements: R22:Harmful if swallowed. R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements:S36:Wear suitable protective clothing. S60:This material and its container must be disposed of as hazardous waste. S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3077 9/PG 3
RTECS: YM3720000

Poison by subcutaneous, intraduodenal, intraperitoneal, and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NO_x and Br⁻. See also BROMIDES.

Toxicity of of Atropine methobromide (CAS NO.2870-71-5):

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	intravenous	118mg/kg (118mg/kg)		Drugs in Japan Vol. -, Pg. 1172, 1990.
guinea pig	LD50	subcutaneous	358mg/kg (358mg/kg)		Drugs in Japan Vol. -, Pg. 1172, 1990.
mouse	LD50	intraperitoneal	75mg/kg (75mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA	Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 1727, 1971.
mouse	LD50	intravenous	9950ug/kg (9.95mg/kg)		Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 53, Pg. 1125, 1957.
mouse	LD50	oral	1640mg/kg (1640mg/kg)		Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 53, Pg. 1125, 1957.
mouse	LD50	subcutaneous	242mg/kg (242mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1132, 1968.
rat	LD50	intraduodenal	312mg/kg (312mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.
rat	LD50	oral	1050mg/kg (1050mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.
rat	LD50	subcutaneous	1800mg/kg (1800mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.