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Home > products > Piperazine, 1-((1-phenylcyclohexyl)acetyl)-4-(2-phenylethyl)-, compd. with L-ascorbic acid

Piperazine, 1-((1-phenylcyclohexyl)acetyl)-4-(2-phenylethyl)-, compd. with L-ascorbic acid cas no:36431-82-0

Synonyms: ASCORBIC ACID

Identification
NamePiperazine, 1-((1-phenylcyclohexyl)acetyl)-4-(2-phenylethyl)-, compd. with L-ascorbic acid
CAS36431-82-0
SynonymsASCORBIC ACID
Molecular FormulaC32H42N2O7
Molecular Weight0
Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo intravenous 2300mg/kg/2D (2300mg/kg) BLOOD: OXIDANT RELATED (GPD DEFICIENT) ANEMIA Annals of Internal Medicine. Vol. 82, Pg. 810, 1975.
mouse LD50 intraperitoneal 643mg/kg (643mg/kg)   Progress in Mutation Research. Vol. 1, Pg. 682, 1981.
mouse LD50 intravenous 518mg/kg (518mg/kg)   Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 269, 1970.
mouse LD50 oral 3367mg/kg (3367mg/kg)   National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
rat LD50 intravenous > 4gm/kg (4000mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 131, 1976.
rat LD50 oral 11900mg/kg (11900mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 131, 1976.
rat LD50 subcutaneous > 10gm/kg (10000mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 131, 1976.
women LDLo intravenous 900mg/kg (900mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" Archives of Internal Medicine. Vol. 145, Pg. 950, 1985.

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