37517-30-9|Butanamide,N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-Products Supply

Butanamide,N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]- cas no:37517-30-9

Synonyms: (+-)-3'-Acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide;(RS)-Acebutolol;Monitan;dl-Acebutolol;

Identification

NameButanamide,N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-
CAS37517-30-9
Synonyms(+-)-3'-Acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide;(RS)-Acebutolol;Monitan;dl-Acebutolol;
EINECS(EC#)253-539-0
Molecular FormulaC₁₈H₂₈N₂O₄
Molecular Weight336.48

Chemical Properties

AppearanceCrystals.
refractive index1.542
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Safety Data

Safety

Moderately toxic by intravenous route. Human systemic effects by ingestion: developmental abnormalities of the cardiovascular and respiratory systems; effects on newborn in biochemical and metabolic abnormalities and reduced growth statistics. A human teratogen. When heated to decomposition it emits toxic fumes of NO_x. A beta-adrenergic blocker.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	4mg/kg (4mg/kg)	CARDIAC: CHANGE IN RATE VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION KIDNEY, URETER, AND BLADDER: CHANGES IN BLOOD VESSELS OR IN CIRCULATION OF KIDNEY	Masui to Sosei. Anesthesia and Resuscitation. Vol. 16, Pg. 13, 1980.
man	TDLo	oral	137mg/kg/24D- (137mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION	Annals of Internal Medicine. Vol. 111, Pg. 533, 1989.
mouse	LD50	intravenous	75200ug/kg (75.2mg/kg)		Nouvelle Presse Medicale. Vol. 7, Pg. 3258, 1978.
mouse	LD50	subcutaneous	125mg/kg (125mg/kg)		Cesko-Slovenska Farmacie. Vol. 42, Pg. 82, 1993.
women	TDLo	oral	109mg/kg/22D- (109mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION	Annals of Internal Medicine. Vol. 111, Pg. 533, 1989.
women	TDLo	oral	152mg/kg (152mg/kg)	CARDIAC: CHANGE IN CONDUCTION VELOCITY VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION	Journal of Toxicology, Clinical Toxicology. Vol. 20, Pg. 69, 1983.

supplier list

Chemner Pharma: Tel:+86-(23)-62482345; Address: 668# International Exhibtion and Conference Center, Chongqing, Sichuan 400060,

Conier Chem & Pharma Co.,Ltd.: Tel:+86-(23)-62922305; Address: 24 South Section 1, Yihuan Road, Chengdu, Sichuan 610065,

Manus Aktteva: Tel:+91-(79)-65123395; Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006,

LGM Pharmaceuticals Inc.: Tel:01-800-8818210; Address: 3200 West End Ave. Suite #500

YiPeng Chemical: Tel:571 85376369; Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China

Shanghai Longsheng chemical Co.,Ltd: Tel:86-21-35325969; Address: No.3,Yuanjiang Road,Minhang District Shanghai,China

HangZhou Peak Chemical Co.,Ltd: Tel:+86-571-88233073; Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China

Hangzhou Amazingchem Co., Ltd: Tel:+86-571-85155437; Address: Rm 409 Wenxin Building No.207, Wen'er Road, Hangzhou, China

China Langchem Inc.: Tel:+86-(21)-58956006; Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203,

Shijiazhuang Tianyue Fine Chemicals Co., Ltd.: Tel:+86-(311)-86597288, 88120366; Address: 8# Dongning Rd, Gaocheng, Hebei,

Shanghai Sochem International Co., Ltd.: Tel:; Address:

AOKChem Co., Ltd.: Tel:+86-(21)-50791030 / 68712331; Address: Room 203, Block D, No.333 Cailun Road, Zhangjiang High-tech Park, Shanghai 201203,

Varda Biotech Pvt. Ltd.: Tel:+91-(22)-6693 5686; Address: #110 & 111 Kartik Complex, New Link Road, Andheri (W), Mumbai, Maharashtra 400 053,

Hangzhou Yipeng(Chem) Tech.Co., Ltd.: Tel:+86-(571)-8537 6369; Address: Building 4, High-tech Industrial Park, No.588 Feijiatang Road, Xiacheng District, Hangzhou, Zhejiang,

S.S.T. Corporation: Tel:+1-(973)-473-4300; Address: 635 Brighton Road, Clifton, New Jersey 07012,

Butanamide,N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]- cas no:37517-30-9

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