4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-,1-[(ethoxycarbonyl)oxy]ethyl ester, hydrochloride (1:1), (2S,5R,6R)- cas no:37661-08-8
Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-,1-[(ethoxycarbonyl)oxy]ethyl ester, monohydrochloride, [2S-[2a,5a,6b(S*)]]-; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-,1-[(ethoxycarbonyl)oxy]ethyl ester, monohydrochloride, (2S,5R,6R)- (9CI);Ambacamp; Ambaxin; Bacacil; Bacampicillin-hydrochloride; Bacampicine;Becampicillin hydrochloride; Penglobe; Spectrobid
Name4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-,1-[(ethoxycarbonyl)oxy]ethyl ester, hydrochloride (1:1), (2S,5R,6R)-
CAS37661-08-8
Synonyms4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-,1-[(ethoxycarbonyl)oxy]ethyl ester, monohydrochloride, [2S-[2a,5a,6b(S*)]]-; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-,1-[(ethoxycarbonyl)oxy]ethyl ester, monohydrochloride, (2S,5R,6R)- (9CI);Ambacamp; Ambaxin; Bacacil; Bacampicillin-hydrochloride; Bacampicine;Becampicillin hydrochloride; Penglobe; Spectrobid
EINECS(EC#)253-580-4
Molecular FormulaC21H27 N3 O7 S . Cl H
Molecular Weight502.03
Safety
Poison by intraperitoneal and intravenous routes. Mildly toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
176mg/kg (176mg/kg) |
BEHAVIORAL: EXCITEMENT
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Chemotherapy Vol. 27(Suppl, |
| mouse |
LD50 |
intravenous |
184mg/kg (184mg/kg) |
BEHAVIORAL: EXCITEMENT
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Chemotherapy Vol. 27(Suppl, |
| mouse |
LD50 |
oral |
8529mg/kg (8529mg/kg) |
BEHAVIORAL: EXCITEMENT
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Chemotherapy Vol. 27(Suppl, |
| mouse |
LD50 |
subcutaneous |
9475mg/kg (9475mg/kg) |
BEHAVIORAL: EXCITEMENT
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Chemotherapy Vol. 27(Suppl, |
| rat |
LD50 |
intravenous |
176mg/kg (176mg/kg) |
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Chemotherapy Vol. 27(Suppl, |
| rat |
LD50 |
oral |
10gm/kg (10000mg/kg) |
|
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 1735, 1981. |
| rat |
LD50 |
subcutaneous |
10gm/kg (10000mg/kg) |
|
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 1735, 1981. |
